Description

Fosfomycin Calcium CAS NO 26472-47-9 is the calcium salt of the broad-spectrum antibiotic fosfomycin, a critical active pharmaceutical ingredient (API) used in the formulation of anti-infective medications. Its primary value lies in its unique bactericidal mechanism, which inhibits bacterial cell wall synthesis and is effective against a range of Gram-positive and Gram-negative pathogens. This compound is essential for pharmaceutical manufacturers and R&D facilities developing oral antibiotic treatments, particularly for uncomplicated urinary tract infections (UTIs).

Application

• Pharmaceutical API: Primary use as the active ingredient in the manufacture of oral antibiotic formulations, specifically fosfomycin trometamol prodrugs.
• Veterinary Medicine: Formulation of antibacterial treatments for livestock and companion animals.
• Clinical Research: Serves as a reference standard and key intermediate in antimicrobial drug discovery and development programs.
• Antibiotic Combination Therapies: Used in research and development of combination drugs to combat antibiotic-resistant bacteria.
• Microbiological Studies: Employed in laboratory settings for studying bacterial resistance mechanisms and efficacy testing.

Basic Information

Product Name	Fosfomycin Calcium
CAS No.	26472-47-9
Molecular Formula	C3H5CaO4P
Molecular Weight	176.12 g/mol
Synonyms	Fosfomycin Calcium Salt; Calcium (1R,2S)-1,2-epoxypropylphosphonate; (-)-(1R,2S)-1,2-Epoxypropylphosphonic Acid Calcium Salt; Phosphomycin Calcium; MK-0955 Calcium Salt; Fosfomycin Calcium (1:1); Fosfomycin Ca; Antibiotic MK 955 Calcium Salt
EINECS	Contact for details

Quality Control

Our Fosfomycin Calcium is produced under strict quality management systems to ensure it meets the rigorous standards required for pharmaceutical intermediates. We offer material compliant with major pharmacopoeial monographs, including USP and EP. Every batch undergoes comprehensive analytical testing, and a Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided to guarantee traceability and consistency for your manufacturing processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water Content (KF)	≤ 2.0%
pH (5% solution)	6.0 - 8.0
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.