Description

2-Bromo-3-Methylbutanoyl Bromide is a versatile and highly reactive acyl bromide derivative, essential for introducing the branched 3-methylbutanoyl moiety into target molecules. Its primary value lies in its role as a key synthetic intermediate for constructing complex organic frameworks, particularly in pharmaceutical research and fine chemical synthesis. This compound is critically needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced material industries for applications such as active pharmaceutical ingredient (API) development and specialty polymer synthesis.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of novel drug candidates, particularly those requiring branched-chain acyl groups.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides where specific steric and electronic properties are needed.
• Peptide Mimetics & Modifications: Employed to acylate amino groups or modify peptide backbones to enhance stability or biological activity.
• Material Science: Serves as a monomer or cross-linking agent in the synthesis of specialty polymers with unique thermal or mechanical properties.
• Ligand & Catalyst Development: Utilized to prepare sophisticated ligands for asymmetric catalysis and organometallic complexes.
• Chemical Biology Probes: Acts as a reactive handle for labeling or modifying biomolecules in proteomics and diagnostic research.

Basic Information

Product Name	2-Bromo-3-Methylbutanoyl Bromide
CAS No.	26464-05-1
Molecular Formula	C5H8Br2O
Molecular Weight	243.93 g/mol
Synonyms	3-Methyl-2-bromobutanoyl bromide; 2-Bromo-3-methylbutyryl bromide; α-Bromo-β-methylbutyryl bromide; 2-Bromo-3-methylbutanoic acid bromide; Butanoyl bromide, 2-bromo-3-methyl-; Isovaleric acid, 2-bromo-, bromide
EINECS	Contact for details

Quality Control

Our 2-Bromo-3-Methylbutanoyl Bromide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chromatography (HPLC/GC) and spectroscopic methods (NMR, IR), to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature and reactivity as a strong acid/organic solvent, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent degradation. Keep away from heat, open flames, and incompatible materials such as bases, alcohols, and amines.

Specification

Item	Specification
Appearance	Clear, colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.