Description

2-Methyl-4-(Trifluoromethyl)Furan-3-Carboxylic Acid is a high-value fluorinated heterocyclic building block, prized for its unique combination of a furan ring and a trifluoromethyl group. This structure is critical for modulating the physicochemical properties of target molecules, enhancing their metabolic stability, lipophilicity, and bioavailability. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and advanced intermediates.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly in medicinal chemistry programs targeting CNS, anti-inflammatory, and antiviral applications.
• Agrochemical Synthesis: Used in the creation of advanced herbicides, fungicides, and insecticides, where the trifluoromethyl group contributes to improved efficacy and environmental profile.
• Material Science Research: Serves as a precursor for specialty polymers, liquid crystals, and organic electronic materials due to its electron-withdrawing characteristics.
• Chemical Biology & Proteomics: Employed as a versatile building block for designing chemical probes and activity-based protein profiling (ABPP) agents.
• Custom Synthesis & Contract Manufacturing: An essential starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.

Basic Information

Product Name	2-Methyl-4-(Trifluoromethyl)Furan-3-Carboxylic Acid
CAS No.	26431-53-8
Molecular Formula	C7H5F3O3
Molecular Weight	194.11 g/mol
Synonyms	2-Methyl-4-(trifluoromethyl)-3-furancarboxylic acid; 3-Furancarboxylic acid, 2-methyl-4-(trifluoromethyl)-; 4-(Trifluoromethyl)-2-methylfuran-3-carboxylic acid; 2-Methyl-4-trifluoromethylfuran-3-carboxylic acid; 2-Methyl-4-(trifluoromethyl)-3-furoic acid; 2-Methyl-α,α,α-trifluoro-3-furancarboxylic acid
EINECS	Contact for details

Quality Control

Our production of 2-Methyl-4-(Trifluoromethyl)Furan-3-Carboxylic Acid adheres to stringent in-process controls and final release testing to ensure batch-to-batch consistency and high purity. We employ advanced analytical techniques including HPLC, GC, NMR, and MS for comprehensive characterization. A Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment. Our quality system supports compliance with cGMP and ISO standards for pharmaceutical and industrial applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (GC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.