Description

3,5-Dimethyl-3'-Isopropyl-L-Thyronine is a synthetic thyroid hormone analog, a key intermediate in pharmaceutical research and development. This compound is valued for its structural specificity, enabling precise studies on thyroid receptor activity and metabolic pathways. It is primarily utilized by research institutions and pharmaceutical companies engaged in endocrinology research and the development of novel therapeutic agents.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of novel thyroid hormone receptor agonists and antagonists for therapeutic development.
• Biochemical Research: Used as a reference standard and active compound in studies investigating thyroid hormone action, metabolism, and receptor binding affinity.
• Endocrinology Studies: Employed in vitro and in vivo models to explore metabolic regulation, cardiac function, and cholesterol metabolism mediated by thyroid pathways.
• Diagnostic Agent Development: Serves as a precursor or competitor in the development of assays and diagnostic tools for thyroid function.

Basic Information

Product Name	3,5-Dimethyl-3'-Isopropyl-L-Thyronine
CAS No.	26384-44-1
Molecular Formula	C15H21NO4
Molecular Weight	279.33 g/mol
Synonyms	3,5-Dimethyl-3'-isopropylthyronine; DIMIT; 3'-Isopropyl-3,5-dimethyl-L-thyronine; (2S)-2-Amino-3-[4-(4-hydroxy-3-isopropylphenoxy)-3,5-dimethylphenyl]propanoic acid; SK&F L-94901; 3,5-Dimethyl-3'-isopropyl-L-thyronine; 3,5-Dimethyl-3'-isopropylthyronine
EINECS	Contact for details

Quality Control

Our 3,5-Dimethyl-3'-Isopropyl-L-Thyronine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and development applications. A Certificate of Analysis (COA) detailing specific results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/IR)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Optical Rotation	Contact for details
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.