Description

3'-Deoxy-3'--C-Methyladenosine is a chemically modified nucleoside analog of significant interest in pharmaceutical research and development. This compound serves as a crucial building block and intermediate for the synthesis of novel antiviral and anticancer therapeutics. It is primarily utilized by research institutions, pharmaceutical companies, and biotechnology firms engaged in drug discovery programs targeting RNA viruses and specific oncological pathways. The high-purity material is essential for ensuring the reproducibility and efficacy of preclinical and clinical studies.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the development of nucleoside-based antiviral drugs.
• Antiviral Research: Investigated for its potential activity against a range of RNA viruses due to its mechanism as a chain terminator.
• Oncology Research: Studied for its application in creating prodrugs and targeted cancer therapies that interfere with cellular nucleotide metabolism.
• Biochemical Tool: Used in enzymatic studies to understand polymerase fidelity and inhibition mechanisms.
• Medicinal Chemistry: Serves as a scaffold for structure-activity relationship (SAR) studies to optimize pharmacokinetic properties.
• Reference Standard: Employed as a high-purity analytical standard for quality control and method validation in API manufacturing.

Basic Information

Product Name	3'-Deoxy-3'--C-Methyladenosine
CAS No.	26383-05-1
Molecular Formula	C₁₁H₁₅N₅O₃
Molecular Weight	265.27 g/mol
Synonyms	3'-Deoxy-3'-C-methyladenosine; 3'-C-Methyladenosine; 3'-Deoxy-3'-methyladenosine; 9-[(3-Deoxy-3-C-methyl-β-D-ribofuranosyl)]adenine; 3'-Methyl-3'-deoxyadenosine; Adenosine, 3'-deoxy-3'-C-methyl-; 3'-C-Me-Ado
EINECS	Contact for details

Quality Control

Our 3'-Deoxy-3'--C-Methyladenosine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity, suitable for research and development applications. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing purity, identity, and impurity profiles as determined by advanced analytical techniques. Our quality commitment aligns with the standards expected for pharmaceutical intermediates, ensuring reliability for your critical projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.