Description

Cetyl Chloroformate CAS NO 26272-90-2 is a high-purity, long-chain alkyl chloroformate ester, serving as a versatile and critical acylating and coupling agent in advanced organic synthesis. Its primary value lies in its ability to introduce the cetyl (hexadecyl) group or act as a protective reagent for amines and alcohols, facilitating the production of specialized intermediates. This compound is essential for research and manufacturing chemists in the pharmaceutical, agrochemical, and specialty chemical industries who require reliable, high-quality building blocks for complex molecule assembly.

Application

• Pharmaceutical Intermediate Synthesis: Key reagent for introducing lipophilic cetyl chains into drug molecules to modify solubility and bioavailability.
• Peptide Coupling Agent: Used in the synthesis of peptides and amides as an activating agent for carboxylic acids.
• Protective Group Chemistry: Effective for the temporary protection of amine and alcohol functional groups during multi-step synthetic sequences.
• Agrochemical Production: Employed in the manufacture of specialized pesticides and herbicides that require long alkyl chain components.
• Polymer Modification: Utilized to functionalize polymers and surfaces with cetyl groups for specific material properties.
• Surfactant & Lubricant Additive Synthesis: Serves as a precursor in creating specialized surfactants and lubricant additives.

Basic Information

Product Name	Cetyl Chloroformate
CAS No.	26272-90-2
Molecular Formula	C₁₇H₃₃ClO₂
Molecular Weight	304.90 g/mol
Synonyms	Hexadecyl chloroformate; Palmitoyl chloroformate; n-Hexadecyl chloroformate; Chloroformic acid cetyl ester; Cetyl chlorocarbonate; CETCF; Carbonochloridic acid, hexadecyl ester
EINECS	247-549-7

Quality Control

Our Cetyl Chloroformate is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including assay by titration and impurity profile analysis by GC/HPLC, to ensure it meets the high-purity standards required for sensitive synthetic applications. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at temperatures between 2°C and 8°C (refrigerated) to maximize stability. Due to its hygroscopic (moisture-sensitive) nature and reactivity with strong acids/organic solvents, it must be kept under an inert atmosphere (e.g., nitrogen or argon) and separated from incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC/Titration)	≥ 97.0%
Cetyl Alcohol (GC)	≤ 1.0%
Acidity (as HCl)	≤ 0.5%
Water Content (KF)	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.