Description

2',3'-Dideoxy-2',3'-Dehydrothymidine 5'-Triphosphate is a modified nucleoside triphosphate analog, a critical building block for advanced biochemical research and development. This compound is essential for studying viral replication mechanisms, particularly as a chain terminator in nucleic acid synthesis. It is primarily utilized by research institutions, pharmaceutical R&D departments, and diagnostic kit manufacturers focused on virology and molecular biology. The product is supplied to the global market with a focus on high purity and batch-to-batch consistency for reliable experimental results.

Application

• Biochemical Research: Used as a substrate analog in enzymatic studies of DNA and RNA polymerases.
• Antiviral Drug Development: Serves as a key intermediate or reference standard in the research of nucleoside reverse transcriptase inhibitors (NRTIs).
• Molecular Diagnostics: Employed in the development of probes and assays for detecting specific viral sequences.
• Enzymology Studies: Acts as a chain-terminating nucleotide to investigate polymerase fidelity and kinetics.
• Academic Research: Fundamental tool for university labs studying retroviruses like HIV and related virology.
• Biotech Reagent Production: A critical raw material for manufacturers of high-purity biochemical kits and reagents.

Basic Information

Product Name	2',3'-Dideoxy-2',3'-Dehydrothymidine 5'-Triphosphate
CAS No.	26194-89-8
Molecular Formula	C10H14N2O13P3
Molecular Weight	487.13 g/mol
Synonyms	d4TTP; Stavudine Triphosphate; 2',3'-Didehydro-2',3'-dideoxythymidine 5'-triphosphate; 1-((2R,4S,5S)-4-Hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-methylpyrimidine-2,4(1H,3H)-dione 5'-(trihydrogen triphosphate); Stavudine 5'-triphosphate; Anti-HIV agent d4TTP; Thymidine 2',3'-didehydro-2',3'-dideoxy-5'-triphosphate
EINECS	Contact for details

Quality Control

Our 2',3'-Dideoxy-2',3'-Dehydrothymidine 5'-Triphosphate is manufactured under strict quality control protocols to ensure it meets the exacting standards required for life science research. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles, verified by techniques such as HPLC and NMR. We are committed to supplying material that supports reproducible scientific outcomes, with specifications tailored for research and diagnostic applications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability. For long-term storage, keep desiccated.

Specification

Item	Specification
Appearance	White to off-white powder or solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 3.0%
Solubility	Soluble in water, slightly soluble in methanol

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.