Description

7-Hydroxycholesterol-3-Stearate is a sterol ester derivative of significant interest in biochemical and pharmaceutical research. This compound serves as a crucial intermediate and reference standard for studying cholesterol metabolism, oxidative stress, and lipid signaling pathways. It is primarily utilized by research institutions, pharmaceutical developers, and advanced material scientists working on lipidomics, biomarker discovery, and novel drug delivery systems.

Application

• Biochemical Research: Used as a reference standard and intermediate in studies of cholesterol oxidation products (oxysterols) and their biological activity.
• Pharmaceutical Development: Acts as a key starting material or analytical standard in the synthesis and quality control of sterol-based active pharmaceutical ingredients (APIs).
• Lipidomics & Biomarker Analysis: Employed in mass spectrometry and chromatography as a calibration standard for quantifying oxysterols in biological samples.
• Academic Research: Facilitates investigations into atherosclerosis, neurodegenerative diseases, and other conditions linked to oxidative cholesterol metabolism.
• Advanced Material Science: Potential use in the development of specialized lipid nanoparticles (LNPs) and other delivery vehicles for bioactive compounds.

Basic Information

Product Name	7-Hydroxycholesterol-3-Stearate
CAS No.	26108-71-4
Molecular Formula	C₄₅H₈₀O₃
Molecular Weight	669.1 g/mol
Synonyms	7-Hydroxycholesteryl Stearate; Cholest-5-en-3β-ol, 7-hydroxy-, 3-stearate; 7-Hydroxycholesterol 3-Stearate; 7α-Hydroxycholesterol Stearate; 7β-Hydroxycholesterol Stearate; 7-HC Stearate; 7-Hydroxycholesteryl Octadecanoate; Oxysterol Stearate Ester
EINECS	Contact for details

Quality Control

Our 7-Hydroxycholesterol-3-Stearate is produced under strict quality management protocols to ensure high purity and batch-to-batch consistency, suitable for sensitive research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry standards for research chemicals, and custom purity grades or analytical services are available to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at 2-8°C to minimize oxidation and degradation. For long-term storage, keep the material at -20°C. The container should be kept in a cool, dry, and well-ventilated area away from incompatible substances.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥95.0%
Melting Point	Contact for details
Loss on Drying	≤1.0%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.