Description

5'-Iodo-5'-Deoxythymidine is a halogenated nucleoside analog of significant interest in pharmaceutical research and development. This compound serves as a crucial synthetic intermediate and a versatile building block for the creation of novel antiviral and anticancer agents. It is primarily utilized by research institutions, pharmaceutical companies, and fine chemical manufacturers engaged in nucleoside chemistry and drug discovery programs.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel antiviral and anticancer nucleoside analogs.
• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies related to DNA synthesis and repair mechanisms.
• Probe Development: Serves as a precursor for radiolabeled (e.g., 125I) compounds used in molecular imaging and diagnostic assays.
• Antiviral Agent Synthesis: Intermediate in the development of potential therapeutics targeting viral polymerases.
• Academic Research: Employed in organic synthesis and medicinal chemistry projects exploring structure-activity relationships.
• Reference Standard: Used as a high-purity analytical standard for quality control and method validation in laboratories.

Basic Information

Product Name	5'-Iodo-5'-Deoxythymidine
CAS No.	25953-14-4
Molecular Formula	C10H13IN2O5
Molecular Weight	368.13 g/mol
Synonyms	5'-Iodo-2'-deoxythymidine; 5'-Iodo-5'-deoxythymidine; 1-(5-Deoxy-5-iodo-β-D-ribofuranosyl)thymine; 5-Iodo-5'-deoxythymidine; 5'-IDT; 5'-Iodothymidine; Thymidine, 5'-iodo-5'-deoxy-; 5'-Deoxy-5'-iodothymidine
EINECS	Contact for details

Quality Control

Our 5'-Iodo-5'-Deoxythymidine is manufactured under strict quality control protocols to ensure high purity and batch-to-batch consistency, suitable for research and development applications. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing purity, identity, and impurity profiles. Our quality systems are designed to meet the stringent requirements of the pharmaceutical and fine chemical industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.