Description

3-Bromothiophene-2-Carbonyl Chloride is a high-purity, reactive organic intermediate essential for advanced chemical synthesis. Its value lies in its dual functional groups—the acid chloride and the bromo substituent—which enable precise, sequential derivatization to construct complex heterocyclic systems. This compound is critically needed by pharmaceutical R&D teams and fine chemical manufacturers for developing active pharmaceutical ingredients (APIs), agrochemicals, and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel thiophene-based drug candidates, including kinase inhibitors and antiviral agents.
• Agrochemical Synthesis: Used in creating advanced herbicides and fungicides with thiophene cores for enhanced efficacy.
• Material Science: Serves as a precursor for functionalized polymers and organic electronic materials, such as conductive polymers and OLED components.
• Ligand and Catalyst Development: Employed to synthesize specialized ligands for transition metal catalysis and organocatalysts.
• Custom Chemical Synthesis: A versatile starting material for contract research organizations (CROs) and CDMOs producing bespoke compounds for clients.
• Academic Research: Used in organic chemistry laboratories to explore new heterocyclic reactions and methodologies.

Basic Information

Product Name	3-Bromothiophene-2-Carbonyl Chloride
CAS No.	25796-68-3
Molecular Formula	C5H2BrClOS
Molecular Weight	225.49 g/mol
Synonyms	2-Bromo-3-thiophenecarbonyl chloride; 3-Bromothiophene-2-carboxylic acid chloride; 2-Bromothiophene-3-carbonyl chloride; 3-Bromo-2-thiophenecarbonyl chloride; 3-Bromothiophene-2-carboxyl chloride; 2-Thiophenecarbonyl chloride, 3-bromo-; 3-Bromothiophene-2-carbonylchloride
EINECS	Contact for details

Quality Control

Our 3-Bromothiophene-2-Carbonyl Chloride is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC, to ensure high chemical purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with each shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic and moisture-sensitive nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening. Keep away from strong bases, oxidizing agents, and sources of ignition.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.