Description

N6,N6-Dimethyl-4’-Thio-Adenosine is a chemically modified nucleoside analog, distinguished by its dimethylated amino group and thio-substituted ribose moiety. This structural modification is critical for its role as a valuable biochemical tool and a key intermediate in pharmaceutical research and development. It is primarily utilized by researchers and manufacturers in the life sciences sector, particularly those focused on nucleotide chemistry, enzyme inhibition studies, and the synthesis of novel therapeutic agents.

Application

• Biochemical Research: Serves as a crucial intermediate or reference standard in studies involving adenosine receptors, methyltransferases, and sulfur metabolism pathways.
• Pharmaceutical Intermediates: Used in the synthesis of more complex nucleoside-based drug candidates targeting various diseases.
• Enzyme Inhibition Studies: Acts as a potential inhibitor or substrate analog for enzymes that interact with natural adenosine, aiding in mechanistic studies.
• Nucleotide Chemistry Development: Provides a modified scaffold for exploring structure-activity relationships (SAR) in medicinal chemistry programs.
• Diagnostic Reagent Synthesis: Can be utilized in the development of specialized probes and reagents for molecular diagnostics.

Basic Information

Product Name	N6,N6-Dimethyl-4’-Thio-Adenosine
CAS No.	25795-69-1
Molecular Formula	C12H17N5O3S
Molecular Weight	311.36 g/mol
Synonyms	4'-Thioadenosine, N6,N6-dimethyl-; 4'-Thio-N6,N6-dimethyladenosine; 6-(Dimethylamino)-9-(4-thio-β-D-ribofuranosyl)-9H-purine; N6,N6-Dimethyl-4'-thioadenosine; 4'-Thio-N6,N6-dimethyladenosine; 6-Dimethylaminopurine 4'-thioriboside
EINECS	Contact for details

Quality Control

Our N6,N6-Dimethyl-4’-Thio-Adenosine is produced under stringent quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, MS). We provide Certificates of Analysis (COA) with each shipment, detailing all relevant specifications to ensure traceability and batch-to-batch consistency for your research and production needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.