Description

3'-Deoxy-3'-(Dimethylamino)-N,n-Dimethyladenosine is a chemically modified nucleoside analog of significant interest in pharmaceutical research and development. This compound serves as a critical intermediate or reference standard in the synthesis of novel therapeutic agents, particularly those targeting viral and oncological pathways. It is primarily utilized by research institutions, pharmaceutical companies, and contract development and manufacturing organizations (CDMOs) engaged in antiviral and anticancer drug discovery programs.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of nucleoside-based antiviral and anticancer prodrugs.
• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies to investigate RNA polymerase and other nucleoside-processing enzymes.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.
• Medicinal Chemistry: A versatile scaffold for structure-activity relationship (SAR) studies to optimize drug potency and selectivity.
• Antiviral Agent Development: Investigated for potential activity against a range of RNA viruses due to its modified sugar moiety.
• Oncology Research: Explored for incorporation into oligonucleotides or as a standalone agent to disrupt cancer cell proliferation.

Basic Information

Product Name	3'-Deoxy-3'-(Dimethylamino)-N,n-Dimethyladenosine
CAS No.	25787-42-2
Molecular Formula	C14H21N7O3
Molecular Weight	335.36 g/mol
Synonyms	3'-Deoxy-3'-(dimethylamino)adenosine; 3'-Deoxy-3'-(dimethylamino)-N6,N6-dimethyladenosine; 3'-Amino-3'-deoxy-N,N-dimethyladenosine; 3'-Dimethylamino-3'-deoxy-N,N-dimethyladenosine; Cordycepin analog; 3'-DMA-3'-dA; 3'-(N,N-Dimethylamino)-3'-deoxy-N,N-dimethyladenosine
EINECS	Contact for details

Quality Control

Our 3'-Deoxy-3'-(Dimethylamino)-N,n-Dimethyladenosine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and tests for residual solvents and moisture. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to ensure traceability and compliance with your research or cGMP requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as indicated on the label or COA. Due to its hygroscopic (moisture-sensitive) nature, the container should be kept sealed under an inert atmosphere after opening to maintain stability and prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.