Description

Estrone Glucoside CAS NO 25591-03-1 is a conjugated metabolite of the primary estrogen, estrone, where the hormone is linked to a glucose molecule. This conjugation significantly alters the compound's solubility, bioavailability, and metabolic pathway, making it a critical reference standard and intermediate in endocrine research and pharmaceutical development. It is essential for scientists and manufacturers in the pharmaceutical, biotechnology, and diagnostic sectors who require high-purity biochemicals for hormone metabolism studies, analytical method development, and the synthesis of more complex steroid derivatives.

Application

• Biochemical Research & Reference Standard: Used as a high-purity analytical standard in LC-MS, HPLC, and GC-MS for quantifying estrogen metabolites in biological samples.
• Pharmaceutical Intermediate: Serves as a key starting material or intermediate in the synthesis of specialized steroid-based pharmaceuticals and novel drug candidates.
• Endocrine Disruptor Studies: Employed in environmental and toxicological research to study the fate, transport, and effects of conjugated hormones.
• Diagnostic Kit Development: Utilized in the development and calibration of immunoassays and diagnostic tests for hormonal status and metabolic disorders.
• Metabolism & Pharmacokinetics: A vital tool for investigating Phase II metabolism (glucuronidation/sulfation) pathways and the pharmacokinetic profile of estrogens.

Basic Information

Product Name	Estrone Glucoside
CAS No.	25591-03-1
Molecular Formula	C24H32O7
Molecular Weight	432.51 g/mol
Synonyms	Estrone 3-glucoside; Estrone 3-D-glucopyranoside; 3-Hydroxyestra-1,3,5(10)-trien-17-one 3-glucoside; Estra-1,3,5(10)-trien-17-one, 3-(β-D-glucopyranosyloxy)-; E1G; Estrone-3-β-D-glucoside
EINECS	Contact for details

Quality Control

Every batch of our Estrone Glucoside is manufactured and tested under a strict quality management system. We provide material suitable for research and development use, with specifications typically targeting high purity levels. Certificates of Analysis (COA) detailing identity, purity (by HPLC), and related substance profiles are available for each lot to ensure traceability and compliance with your research protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent absorption of water. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥95.0%
Related Substances (HPLC)	Total impurities ≤5.0%
Water Content (KF)	≤5.0%
Residue on Ignition	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.