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(10α)-2α,3α,16α,20,25-Pentahydroxy-9β-Methyl-19-Norlanost-5-Ene-11,22-Dione CAS NO 25383-26-0


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CAS No.:25383-26-0

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

(10α)-2α,3α,16α,20,25-Pentahydroxy-9β-Methyl-19-Norlanost-5-Ene-11,22-Dione is a highly functionalized norlanostane derivative, a complex triterpenoid scaffold of significant interest in advanced organic synthesis and pharmaceutical research. Its intricate polyhydroxylated structure makes it a valuable key intermediate for developing novel bioactive compounds, particularly in steroid and sapogenin chemistry. This compound is essential for R&D chemists and process development scientists working in pharmaceutical development, natural product synthesis, and the creation of specialized chemical libraries.

Application

  • Pharmaceutical Intermediate: Serves as a critical building block for the synthesis of novel steroid-like drugs and therapeutic agents targeting metabolic and inflammatory pathways.
  • Natural Product Synthesis: Used as a precursor in the semi-synthesis or total synthesis of complex triterpenoids and saponins with potential biological activity.
  • Biochemical Research: Employed as a reference standard or probe in studies investigating enzyme interactions, receptor binding, or metabolic pathways involving lanostane-derived molecules.
  • Process Chemistry Development: Utilized in route scouting and optimization for the scalable production of high-value, complex organic molecules.
  • Chemical Library Construction: Acts as a versatile core structure for generating diverse compound libraries via chemical modification for high-throughput screening in drug discovery.

Basic Information

Product Name (10α)-2α,3α,16α,20,25-Pentahydroxy-9β-Methyl-19-Norlanost-5-Ene-11,22-Dione
CAS No. 25383-26-0
Molecular Formula C₂₉H₄₄O₈
Molecular Weight 532.66 g/mol
Synonyms 19-Norlanost-5-ene-2,3,16,20,25-pentol, 9-methyl-11,22-dione, (2α,3α,9β,10α,16α)-; 9β-Methyl-19-norlanost-5-ene-2α,3α,16α,20,25-pentol-11,22-dione; Polyhydroxylated 19-Norlanostane Dione; 2,3,16,20,25-Pentahydroxy-9-methyl-19-norlanost-5-ene-11,22-dione
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Quality Control

Our production of (10α)-2α,3α,16α,20,25-Pentahydroxy-9β-Methyl-19-Norlanost-5-Ene-11,22-Dione adheres to stringent in-process controls to ensure batch-to-batch consistency and high purity. Every lot is fully characterized using advanced analytical techniques including NMR, HPLC, and MS. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment, supporting cGMP-compliant development work.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which can affect stability and handling properties.

Specification

Item Specification
Appearance White to off-white powder
Identification (IR) Conforms to structure
Identification (HPLC) Retention time matches reference standard
Purity (HPLC) ≥ 95.0%
Water Content (KF) ≤ 2.0%
Residue on Ignition ≤ 0.5%
Heavy Metals ≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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