Description

Phosphonomycin (R)-1-Phenethylamine Salt is a high-purity salt form of the broad-spectrum antibiotic fosfomycin, specifically complexed with (R)-1-phenethylamine. This form is critical for enhancing the stability, solubility, and handling characteristics of the active pharmaceutical ingredient (API) for advanced pharmaceutical manufacturing. It is primarily required by manufacturers in the pharmaceutical and biotechnology sectors for the development and production of antibiotic formulations, particularly for treating serious infections caused by multi-drug resistant bacteria.

Application

• Active Pharmaceutical Ingredient (API) Intermediate: A key chiral building block in the synthesis of high-purity fosfomycin tromethamine and other fosfomycin-based antibiotic drugs.
• Pharmaceutical R&D: Used in research laboratories for developing new antibiotic compounds and studying mechanisms of action against resistant pathogens.
• Veterinary Medicine: Employed in the formulation of antibiotic treatments for bacterial infections in livestock and companion animals.
• Reference Standard: Serves as a certified reference material (CRM) for quality control and analytical method validation in regulatory testing.

Basic Information

Product Name	Phosphonomycin (R)-1-Phenethylamine Salt
CAS No.	25383-07-7
Molecular Formula	C11H18NO4P
Molecular Weight	259.24 g/mol
Synonyms	Fosfomycin (R)-1-Phenethylamine Salt; (1R)-1-Phenylethanaminium (1R,2S)-(1,2-epoxypropyl)phosphonate; (R)-Phenethylamine Fosfomycin Salt; (-)-(1R,2S)-1,2-Epoxypropylphosphonic Acid (R)-1-Phenylethylamine Salt; Antibiotic FR-33289 Salt; Phosphomycin Phenethylamine Salt; (R)-α-Methylbenzylamine Fosfomycin Salt
EINECS	Contact for details

Quality Control

Our Phosphonomycin (R)-1-Phenethylamine Salt is manufactured under strict quality management systems. Each batch is tested to ensure it meets high-purity standards suitable for pharmaceutical applications, with typical purity levels exceeding 98.5%. A comprehensive Certificate of Analysis (COA) is provided with each shipment, detailing results for assay, chiral purity, related substances, residual solvents, and microbiological tests. We support compliance with ICH Q7 guidelines and relevant pharmacopeial standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.5 %
Chiral Purity (HPLC)	≥ 99.0 % (R-isomer)
Related Substances (HPLC)	Total impurities ≤ 1.0%
Water Content (KF)	≤ 0.5 %
Residue on Ignition	≤ 0.1 %
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.