Description

3α,7α,12α-Trihydroxy-5β-Cholane-24-Thioic Acid is a high-purity bile acid derivative, a key intermediate in the synthesis of advanced pharmaceutical compounds and biochemical research reagents. Its specific stereochemistry and functional groups make it a critical building block for developing targeted therapies and diagnostic agents. This compound is essential for research and production facilities in the pharmaceutical, biotechnology, and fine chemical sectors requiring precise molecular structures for metabolic studies and drug development.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel therapeutic agents targeting liver and metabolic pathways.
• Biochemical Research: Used as a reference standard and reagent in studies of bile acid metabolism, transport, and receptor interactions.
• Diagnostic Agent Development: Serves as a starting material for creating labeled compounds used in clinical diagnostics and imaging.
• Enzyme Substrate/Analogue: Employed in enzymatic assays and inhibition studies related to sterol and lipid biochemistry.
• Fine Chemical Synthesis: A specialized building block for constructing complex steroidal and cholanic acid derivatives with high stereochemical fidelity.

Basic Information

Product Name	3α,7α,12α-Trihydroxy-5β-Cholane-24-Thioic Acid
CAS No.	25151-67-1
Molecular Formula	C24H40O5S
Molecular Weight	440.64 g/mol
Synonyms	3α,7α,12α-Trihydroxy-5β-cholan-24-thioic Acid; Taurocholic Acid Thio-Analogue; 5β-Cholan-24-thioic Acid-3α,7α,12α-triol; Cholane-24-thioic Acid, 3,7,12-trihydroxy-, (3α,5β,7α,12α)-; Thiocholic Acid; Taurocholic Acid Thio Derivative; 24-Thiocholic Acid; (3α,5β,7α,12α)-3,7,12-Trihydroxycholan-24-thioic Acid
EINECS	Contact for details

Quality Control

Our 3α,7α,12α-Trihydroxy-5β-Cholane-24-Thioic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, identity confirmation by IR and NMR, and specific tests for related substances and residual solvents. We provide full traceability and Certificates of Analysis (COA) are available upon request to ensure compliance with your research or cGMP-grade specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.