Description

Adenosine, 5'-Sulfamate CAS NO 25030-31-3 is a chemically modified nucleoside analog where the 5'-hydroxyl group of adenosine is replaced by a sulfamate moiety. This structural modification is of significant interest in biochemical and pharmaceutical research, particularly in the study of enzyme inhibition and signal transduction pathways. It serves as a valuable intermediate and reference standard for researchers and manufacturers in the life sciences sector.

Application

• Biochemical Research: Used as a key intermediate in the synthesis of novel adenosine receptor ligands and enzyme inhibitors.
• Pharmaceutical Development: Serves as a building block for potential prodrugs or active pharmaceutical ingredients (APIs) targeting various metabolic and neurological pathways.
• Enzymology Studies: Acts as a substrate analog to investigate the activity and mechanism of sulfotransferases and other nucleoside-metabolizing enzymes.
• Reference Standard: Employed as a high-purity analytical standard for quality control and method development in HPLC and LC-MS assays.
• Academic Research: Utilized in universities and research institutes for fundamental studies in medicinal chemistry and molecular biology.

Basic Information

Product Name	Adenosine, 5'-Sulfamate
CAS No.	25030-31-3
Molecular Formula	C10H14N6O6S
Molecular Weight	346.32 g/mol
Synonyms	5'-Sulfamoyladenosine; Adenosine 5'-Sulfamate; 5'-O-Sulfamoyladenosine; 9-β-D-Ribofuranosyladenine 5'-Sulfamate; NSC 163039; 5'-Deoxy-5'-(sulfamoylamino)adenosine
EINECS	Contact for details

Quality Control

Our Adenosine, 5'-Sulfamate is produced under a rigorous quality management system. Each batch is subjected to comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your research or development specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/IR)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.