Description

8-Hydroxyadenosine 5'-Monophosphate is a modified nucleotide monophosphate derivative of adenosine, featuring a hydroxyl group at the 8-position of the purine ring. This structural modification makes it a valuable biochemical tool and a key intermediate in the study of nucleic acid chemistry, oxidative damage, and enzymatic pathways. It is primarily utilized by research institutions and pharmaceutical companies engaged in nucleotide metabolism research, enzymology studies, and the development of novel therapeutic agents.

Application

• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies, particularly for kinases, phosphatases, and other nucleotide-processing enzymes.
• Nucleic Acid Chemistry: Serves as a critical intermediate in the synthesis of modified oligonucleotides for probing DNA/RNA structure and function.
• Oxidative Stress Studies: Acts as a marker or model compound in research investigating oxidative damage to purine nucleotides.
• Pharmaceutical Development: Employed in the research and development of nucleotide-based drugs, including antivirals and anticancer agents.
• Diagnostic Reagent Manufacturing: Used in the formulation of specialized reagents for diagnostic assays and research kits.
• Metabolic Pathway Analysis: Applied in tracing and understanding specific nucleotide salvage and metabolic pathways within cells.

Basic Information

Product Name	8-Hydroxyadenosine 5'-Monophosphate
CAS No.	25030-04-0
Molecular Formula	C10H14N5O8P
Molecular Weight	363.22 g/mol
Synonyms	8-Hydroxy-AMP; 8-OH-AMP; 8-Oxo-adenosine 5'-monophosphate; 8-Oxo-AMP; Adenosine-8-ol 5'-monophosphate; 8-Hydroxyadenylic acid; 8-HO-Ado-5'-MP; 25030-04-0
EINECS	Contact for details

Quality Control

Our 8-Hydroxyadenosine 5'-Monophosphate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity assessment and spectroscopic methods for structural confirmation, to ensure it meets the high standards required for research and development applications. A Certificate of Analysis (COA) detailing purity, identity, and other critical parameters is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry, cool place. This product is hygroscopic (moisture-sensitive). Allow the container to reach room temperature before opening to minimize moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥95.0%
Water Content (KF)	≤5.0%
Solubility	Soluble in water, DMSO

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.