Description

5ξ-Bufanolide CAS NO 24887-77-2 is a high-purity steroidal compound belonging to the bufanolide class, known for its specific structural configuration. This compound is of significant interest in advanced pharmaceutical research and development due to its potential as a key intermediate or reference standard. It is primarily utilized by research institutions, pharmaceutical companies, and fine chemical manufacturers engaged in the synthesis of novel therapeutic agents and biochemical studies.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of specialized steroidal drugs and bioactive molecules.
• Biochemical Research: Used as a reference standard or probe in studies investigating cardiac glycoside pathways and steroid hormone interactions.
• Reference Material: Employed in analytical laboratories for method development, calibration, and quality control of related compounds.
• Academic Research: Utilized in university and institutional labs for pharmacological and toxicological studies on bufanolide derivatives.
• Fine Chemical Synthesis: Acts as a precursor in the multi-step synthesis of complex natural products and their analogs.

Basic Information

Product Name	5ξ-Bufanolide
CAS No.	24887-77-2
Molecular Formula	C24H34O4
Molecular Weight	386.53 g/mol
Synonyms	5-Epibufanolide; 5ξ-Bufanolide; Bufa-20,22-dienolide, 3β,14-dihydroxy-, (3β,5ξ,14β)-; 3β,14-Dihydroxy-5ξ-bufa-20,22-dienolide; NSC 146061; 5-Epibufalin aglycone
EINECS	Contact for details

Quality Control

Our 5ξ-Bufanolide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing including HPLC, NMR, and mass spectrometry to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with specified parameters. We support research and cGMP-grade requirements upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.