Description

9-β-D-Arabinofuranosyl-n-Hydroxy-9H-Purin-6-Amine CAS NO 24822-51-3 is a chemically modified nucleoside analog, a key intermediate in the synthesis of novel antiviral and anticancer agents. Its value lies in its role as a versatile building block for developing targeted therapeutics, particularly in nucleotide-based drug discovery. This high-purity compound is essential for pharmaceutical R&D laboratories, biotechnology companies, and academic institutions focused on virology and oncology research.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of nucleoside-based antiviral drugs targeting viral polymerases.
• Anticancer Agent Research: Used in the development and screening of novel chemotherapeutic compounds that interfere with DNA/RNA synthesis in cancer cells.
• Biochemical Research: Serves as a substrate or inhibitor in enzymatic studies related to purine metabolism and nucleic acid biochemistry.
• Pro-drug Development: Utilized for creating more bioavailable or targeted pro-drug forms of active nucleoside therapeutics.
• Reference Standard: Employed as a high-purity analytical standard for quality control and method validation in pharmaceutical manufacturing.

Basic Information

Product Name	9-β-D-Arabinofuranosyl-n-Hydroxy-9H-Purin-6-Amine
CAS No.	24822-51-3
Molecular Formula	C₁₀H₁₃N₅O₅
Molecular Weight	283.24 g/mol
Synonyms	9-β-D-Arabinofuranosyl-9H-purin-6-amine, N-Hydroxy-; 6-Amino-9-β-D-arabinofuranosyl-9H-purine; 9-β-D-Arabinofuranosyladenine N-oxide; Ara-A N1-oxide; Vidarabine N1-oxide; 9-β-D-Arabinofuranosyl-6-aminopurine N-oxide; 6-Amino-9-β-D-arabinofuranosylpurine N-oxide
EINECS	Contact for details

Quality Control

Our 9-β-D-Arabinofuranosyl-n-Hydroxy-9H-Purin-6-Amine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and stringent controls for residual solvents and impurities. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with research-grade specifications. Custom synthesis and purity grades (e.g., >98%, >99%) are available to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a desiccated environment to prevent degradation. For long-term storage, consider inert atmosphere packaging.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.