Description

(20R,25R)-20-Acetyl-5α-Spirostane CAS NO 24799-50-6 is a high-purity, steroidal sapogenin derivative characterized by its specific stereochemistry at the 20 and 25 positions. This compound serves as a critical advanced intermediate in the synthesis of complex steroid-based pharmaceuticals and bioactive molecules. It is primarily required by research institutions and pharmaceutical manufacturers engaged in the development of novel therapeutic agents, particularly in the fields of endocrinology and oncology.

Application

• Pharmaceutical Intermediate: A key chiral building block for the synthesis of steroidal drugs and hormone analogs.
• Research & Development: Used in academic and industrial laboratories for studying steroid biosynthesis and metabolism.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.
• Biochemical Research: Employed in the investigation of enzyme inhibitors and receptor binding studies related to steroid pathways.
• Fine Chemical Synthesis: Utilized as a precursor for the preparation of more complex, functionalized spirostane derivatives.

Basic Information

Product Name	(20R,25R)-20-Acetyl-5α-Spirostane
CAS No.	24799-50-6
Molecular Formula	C29H44O5
Molecular Weight	472.66 g/mol
Synonyms	20-Acetyl-5α-spirostan; (20R,25R)-Spirostan-20-yl acetate; 5α-Spirostan-20β-ol, 20-acetate, (20R,25R)-; 20β-Acetoxy-5α-spirostan; 24799-50-6; 20-Acetoxyspirostan; Spirostan-20β-yl acetate
EINECS	Contact for details

Quality Control

Our (20R,25R)-20-Acetyl-5α-Spirostane is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and chiral analysis to confirm stereochemical integrity, ensuring it meets the stringent requirements for pharmaceutical research and development. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Chiral Purity	≥ 99.0% (20R,25R)
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.