Description

(25S)-5α-Spirostan-24-One CAS NO 24744-42-1 is a high-purity steroidal sapogenin derivative, a key intermediate in the synthesis of various bioactive steroid compounds. Its defined stereochemistry at the 25-position makes it a valuable chiral building block for pharmaceutical research and development. This compound is primarily utilized by research institutions and manufacturers in the pharmaceutical, agrochemical, and fine chemical sectors for the development of novel therapeutic agents and specialized chemical products.

Application

• Pharmaceutical Intermediate: A critical chiral precursor in the synthesis of steroidal drugs, including potential anti-inflammatory, hormonal, and cardiovascular agents.
• Research & Development: Used as a reference standard and starting material in academic and industrial laboratories for exploring new synthetic pathways and biological activities.
• Agrochemical Synthesis: Serves as a building block for developing novel plant growth regulators or bioactive agrochemicals with steroidal backbones.
• Fine Chemical Production: Employed in the manufacture of specialized steroidal compounds for various high-value industrial applications.
• Biochemical Research: Utilized in studies investigating enzyme interactions, receptor binding, and metabolic pathways involving steroidal structures.

Basic Information

Product Name	(25S)-5α-Spirostan-24-One
CAS No.	24744-42-1
Molecular Formula	C27H42O4
Molecular Weight	430.62 g/mol
Synonyms	(25S)-5α-Spirostan-24-one; 24-Oxo-5α-spirostan-3β-ol; Tigogenone; (25S)-5α-Spirostan-3β-ol-24-one; 3β-Hydroxy-5α-spirostan-24-one; Tigogenin 24-one; Tigogenone; 5α-Spirostan-24-one (25S-isomer)
EINECS	Contact for details

Quality Control

Our (25S)-5α-Spirostan-24-One is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, IR and NMR for structural confirmation, and specific tests for residual solvents and related substances. We provide full traceability and Certificates of Analysis (COA) are available upon request to ensure compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed and away from moisture and direct light exposure to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Specific Rotation	Contact for details
Loss on Drying	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.