Description

(25R)-5α-Spirostan-25-Ol CAS NO 24744-40-9 is a high-purity steroidal sapogenin derivative, a key intermediate in the synthesis of complex bioactive molecules. Its defined stereochemistry at the 25-position makes it a valuable chiral building block for pharmaceutical research and development. This compound is primarily sought by researchers and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries for the production of steroid-based drugs and other specialized organic compounds.

Application

• Pharmaceutical Intermediate: A critical chiral precursor in the synthesis of steroidal drugs, including potential anti-inflammatory, hormonal, and cardiovascular agents.
• Research & Development: Used in academic and industrial R&D labs for exploring new synthetic pathways and developing novel bioactive compounds.
• Fine Chemical Synthesis: Serves as a building block for creating complex molecules used in agrochemicals and advanced materials.
• Reference Standard: Employed as an analytical standard in quality control laboratories for method development and compound identification.
• Biochemical Studies: Utilized in studies investigating sterol metabolism and the biological activity of sapogenin derivatives.

Basic Information

Product Name	(25R)-5α-Spirostan-25-Ol
CAS No.	24744-40-9
Molecular Formula	C27H44O3
Molecular Weight	416.64 g/mol
Synonyms	(25R)-Spirostan-25-ol; 5α-Spirostan-25-ol, (25R)-; 25R-Spirostanol; (25R)-5α-Spirostan-3β-ol; Tigogenin (Note: Tigogenin is a closely related 25S epimer); Neotigogenin (common name for the 25R epimer); 3β-Hydroxy-(25R)-5α-spirostan; 25R-Spirostan-3β-ol
EINECS	Contact for details

Quality Control

Our (25R)-5α-Spirostan-25-Ol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and chiral analysis to confirm stereochemical integrity, ensuring it meets the high standards required for research and synthesis. A Certificate of Analysis (COA) detailing specific results for identity, purity, and related substances is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its sensitivity to oxidation, it is recommended to store the product under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% (25R isomer)
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.