Description

(23S,25R)-5α-Spirostan-23-Ol CAS NO 24744-36-3 is a high-purity, specific stereoisomer of a spirostan derivative, a key structural motif found in numerous bioactive natural products. This compound serves as a critical advanced pharmaceutical intermediate and a valuable reference standard for research and quality control. It is primarily utilized by pharmaceutical R&D teams, academic research institutions, and manufacturers in the fine chemical sector for the synthesis of steroid-based drugs and novel chemical entities.

Application

• Pharmaceutical Intermediate: A key chiral building block for the synthesis of steroid-based active pharmaceutical ingredients (APIs) and novel drug candidates.
• Reference Standard: Used as a high-purity analytical standard in HPLC, LC-MS, and NMR for method development, validation, and quality assurance in pharmaceutical laboratories.
• Academic & Biotech Research: Employed in medicinal chemistry programs to study structure-activity relationships (SAR) and develop new therapeutic agents targeting hormone receptors or other biological pathways.
• Process Chemistry Development: Serves as a starting material or intermediate in scaling up synthetic routes for complex organic molecules under GMP or non-GMP conditions.
• Fine Chemical Synthesis: Utilized in the custom synthesis of specialized spirostan derivatives for various industrial and research applications.

Basic Information

Item	Detail
Product Name	(23S,25R)-5α-Spirostan-23-Ol
CAS No.	24744-36-3
Molecular Formula	C27H44O3
Molecular Weight	416.64 g/mol
Synonyms	(23S,25R)-5α-Spirostan-23-ol; 23-Hydroxy-5α-spirostan; (23S,25R)-23-Hydroxyspirostan; 5α-Spirostan-23β-ol (specific stereoisomer); Tigogenin derivative; Spirostan-23-ol; 24744-36-3; (23S,25R)-Spirostan-23-ol
EINECS	Contact for details

Quality Control

Our (23S,25R)-5α-Spirostan-23-Ol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis to confirm stereochemical integrity, and spectroscopic identification (NMR, IR, MS). We provide a comprehensive Certificate of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment ensures the material is suitable for demanding applications in pharmaceutical development and analytical research.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). The compound is light-sensitive; prolonged exposure to light should be avoided to maintain stability and purity. Keep the container sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Chiral Purity	≥ 99.0% (by Chiral HPLC)
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.