Description

(23R,25R)-5α-Spirostan-23-Ol CAS NO 24744-35-2 is a high-purity, stereochemically defined spirostan derivative, a key intermediate in the synthesis of bioactive steroids and sapogenins. Its precise stereochemistry at the 23 and 25 positions is critical for ensuring the efficacy and specificity of downstream pharmaceutical and research applications. This compound is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of novel steroid-based therapeutics, hormone analogs, and high-value fine chemicals.

Application

• Pharmaceutical Intermediate: A crucial chiral building block for the synthesis of steroidal drugs, including potential cardiotonic agents and hormone modulators.
• Research & Development: Used in academic and industrial laboratories for studying steroid biosynthesis, structure-activity relationships (SAR), and metabolic pathways.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.
• Fine Chemical Synthesis: Employed in the multi-step synthesis of complex natural products and specialized sapogenin derivatives.
• Biochemical Research: Investigated for its interactions with enzymes and receptors within steroidogenic pathways.

Basic Information

Item	Detail
Product Name	(23R,25R)-5α-Spirostan-23-Ol
CAS No.	24744-35-2
Molecular Formula	C27H44O4
Molecular Weight	432.64 g/mol
Synonyms	(23R,25R)-Spirostan-23-ol; (23R,25R)-5α-Spirostan-23-ol; 23-Hydroxy-5α-spirostan; Tigogenin 23-ol isomer; 5α,23R,25R-Spirostan-23-ol; (23R,25R)-Dihydroxytigogenin; 23R-Hydroxytigogenin; Tigogenin derivative
EINECS	Contact for details

Quality Control

Every batch of (23R,25R)-5α-Spirostan-23-Ol is produced and tested under a strict quality management system to ensure identity, purity, and consistency. Our products undergo rigorous analytical testing, including HPLC, NMR, and specific rotation analysis, to confirm stereochemical purity and meet exacting research-grade standards. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). The product is light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Specific Rotation	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.