Description

(25R,14β)-5α-Spirostane CAS NO 24742-85-6 is a high-purity, steroidal sapogenin derivative characterized by its specific (25R,14β) stereochemistry. This compound serves as a critical advanced intermediate in the synthesis of complex steroid-based pharmaceuticals and bioactive molecules. It is essential for research and development chemists, process chemists, and manufacturers in the pharmaceutical, biotechnology, and fine chemical industries who require a reliable, high-quality building block for creating novel therapeutic agents.

Application

• Pharmaceutical Intermediate: A key chiral building block for the synthesis of steroidal drugs, including corticosteroids, hormones, and other bioactive steroids.
• Research & Development: Used in academic and industrial R&D for exploring new synthetic pathways and developing novel steroid-based compounds with potential therapeutic applications.
• Process Chemistry: Employed in the scale-up and optimization of synthetic routes for active pharmaceutical ingredients (APIs) in a GMP or pilot plant environment.
• Fine Chemical Synthesis: Serves as a precursor for creating specialized steroidal compounds used in agrochemicals, materials science, and other advanced chemical applications.
• Reference Standard: Can be utilized as a high-purity analytical standard for quality control and method development in analytical laboratories.

Basic Information

Product Name	(25R,14β)-5α-Spirostane
CAS No.	24742-85-6
Molecular Formula	C27H44O3
Molecular Weight	416.64 g/mol
Synonyms	(25R)-5α-Spirostan-3β-ol; (25R)-5α-Spirostane-3β-ol; (25R)-Diosgenin; 5α-Spirostan-3β-ol, (25R)-; (25R)-Spirostan-3β-ol; 3β-Hydroxy-(25R)-5α-spirostane; Tigogenin (Note: Tigogenin is a common trade/trivial name for this specific stereoisomer); (25R,14β)-5α-Spirostane
EINECS	Contact for details

Quality Control

Our (25R,14β)-5α-Spirostane is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. We provide full traceability and detailed Certificates of Analysis (COA) with every shipment. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your most critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Melting Point	Contact for details
Loss on Drying	≤0.5%
Specific Rotation	Contact for details
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.