Description

Adenosine 5'-Monophospho-Morpholidate 4-Morpholine-N,N'-Dicyclohexylcarboxamidine Salt is a high-purity, protected nucleotide derivative used as a key reagent in organic synthesis and biochemical research. This compound is critical for the controlled synthesis of nucleotide analogs and oligonucleotides, where it acts as a stable, activated intermediate. It is primarily utilized by research institutions and pharmaceutical companies engaged in nucleic acid chemistry, drug discovery, and the development of antiviral or anticancer therapeutics.

Application

• Oligonucleotide Synthesis: Serves as a crucial activated monomer for the solid-phase or solution-phase synthesis of modified oligonucleotides.
• Nucleotide Analog Production: Used as a building block in the research and development of novel nucleoside and nucleotide analogs with therapeutic potential.
• Biochemical Research: Acts as a substrate or inhibitor in enzymatic studies related to kinases, polymerases, and other nucleotide-binding proteins.
• Pharmaceutical Intermediates: A key starting material in the synthesis pathway for investigational new drugs (INDs) targeting viral or genetic diseases.
• Labeled Compound Synthesis: Facilitates the introduction of isotopic or fluorescent labels into nucleic acid sequences for diagnostic and research applications.

Basic Information

Product Name	Adenosine 5'-Monophospho-Morpholidate 4-Morpholine-N,N'-Dicyclohexylcarboxamidine Salt
CAS No.	24558-92-7
Molecular Formula	C32H53N9O7P
Molecular Weight	706.81 g/mol
Synonyms	AMP-Morpholidate Morpholine Salt; Adenosine 5'-Monophosphomorpholidate 4-Morpholine-N,N'-Dicyclohexylcarboxamidine Salt; Adenosine 5'-(Methylenebisphosphoramidate) Morpholine Salt; 5'-AMP Morpholidate; P1-(Adenosine-5')-P2-(morpholino)phosphoramidate Morpholine Salt; Activated AMP; Adenosine 5'-Monophosphoromorpholidate; Adenosine 5'-Monophosphomorpholidate
EINECS	Contact for details

Quality Control

Our Adenosine 5'-Monophospho-Morpholidate 4-Morpholine-N,N'-Dicyclohexylcarboxamidine Salt is manufactured under strict quality systems to ensure batch-to-batch consistency and high purity for research applications. All products undergo rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability. For long-term storage, consider desiccation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 2.0%
Solubility	Soluble in DMSO, DMF; Slightly soluble in water

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.