Description

N3-Methyl-2'-Deoxyuridine CAS NO 24514-32-7 is a chemically modified nucleoside analog, specifically a methylated derivative of deoxyuridine. This compound is of significant interest in biochemical and pharmaceutical research for its role in studying nucleic acid structure, function, and as a potential precursor in the synthesis of modified oligonucleotides. It serves as a critical building block and research tool for scientists in the fields of medicinal chemistry, molecular biology, and oncology research.

Application

• Nucleic Acid Research: Used as a modified nucleoside building block for the synthesis of oligonucleotides to study DNA structure, stability, and protein interactions.
• Medicinal Chemistry & Drug Discovery: Acts as a key intermediate in the development of novel antiviral and anticancer nucleoside analogs.
• Biochemical Probe Development: Employed to create labeled or tagged nucleotides for tracking and imaging applications in cellular studies.
• Enzymology Studies: Serves as a substrate or inhibitor to investigate the activity and mechanism of thymidylate synthase and other nucleotide-metabolizing enzymes.
• Academic & Pharmaceutical R&D: A fundamental reagent for universities and R&D laboratories exploring epigenetic modifications and DNA damage/repair pathways.

Basic Information

Product Name	N3-Methyl-2'-Deoxyuridine
CAS No.	24514-32-7
Molecular Formula	C10H14N2O5
Molecular Weight	242.23 g/mol
Synonyms	3-Methyl-2'-deoxyuridine; 1-(2-Deoxy-β-D-ribofuranosyl)-3-methyl-2,4(1H,3H)-pyrimidinedione; 3-Methyldeoxyuridine; N3-Methyldeoxyuridine; 2'-Deoxy-3-methyluridine; d3-MeUrd
EINECS	Contact for details

Quality Control

Our N3-Methyl-2'-Deoxyuridine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and tests for residual solvents and moisture. A detailed Certificate of Analysis (COA) is provided with every shipment to ensure traceability and compliance with your research specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.