Description

2,3,4-Tri-o-Acetyl-α-D-Fucopyranosyl Bromide is a high-purity, protected glycosyl bromide derivative, a critical building block in synthetic carbohydrate chemistry. Its primary value lies in its role as a key glycosyl donor for the stereoselective synthesis of complex oligosaccharides and glycoconjugates. This compound is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and life science sectors, particularly for developing novel glycotherapeutics, vaccines, and diagnostic tools.

Application

• Glycosylation Reactions: Acts as a crucial glycosyl donor in Koenigs-Knorr and related glycosylation methodologies for constructing α-linked fucose-containing structures.
• Oligosaccharide Synthesis: A key intermediate in the multi-step synthesis of biologically active oligosaccharides and polysaccharides for research and development.
• Glycoconjugate Production: Used in the preparation of glycoproteins, glycolipids, and neoglycoconjugates for immunological and therapeutic studies.
• Pharmaceutical Intermediates: Serves as a vital precursor in the synthesis of carbohydrate-based active pharmaceutical ingredients (APIs) and prodrugs.
• Chemical Biology Probes: Utilized to create labeled or modified carbohydrate probes for studying carbohydrate-protein interactions and cell surface recognition events.
• Standards and Reference Materials: Provides a high-purity standard for analytical method development and quality control in carbohydrate analysis.

Basic Information

Product Name	2,3,4-Tri-o-Acetyl-α-D-Fucopyranosyl Bromide
CAS No.	24404-52-2
Molecular Formula	C₁₂H₁₇BrO₈
Molecular Weight	369.16 g/mol
Synonyms	2,3,4-Tri-O-acetyl-α-D-fucopyranosyl bromide; α-D-Fucopyranosyl bromide, 2,3,4-triacetate; 1-Bromo-2,3,4-tri-O-acetyl-α-D-fucopyranose; Tri-O-acetyl-α-D-fucopyranosyl bromide; α-D-Fucopyranosyl bromide triacetate; 2,3,4-Triacetyl-α-D-fucopyranosyl bromide; (2R,3S,4S,5R,6S)-2-(Acetyloxymethyl)-6-bromo-3,4,5-tris(acetyloxy)oxane
EINECS	Contact for details

Quality Control

Every batch of 2,3,4-Tri-o-Acetyl-α-D-Fucopyranosyl Bromide is manufactured and tested under strict quality management protocols to ensure identity, purity, and consistency. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) are available upon request, providing detailed results for all critical parameters including assay, optical rotation, and impurity profile.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C (refrigerated) or as indicated on the label or COA. This material is hygroscopic (moisture-sensitive) and light-sensitive; containers must be kept tightly sealed in a desiccated environment to prevent decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Optical Rotation [α]²⁰D	Contact for details
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.