Description

5-Chlorotubercidin is a chemically modified nucleoside analog that serves as a potent and selective inhibitor of adenosine kinase. This compound is valued for its ability to modulate adenosine signaling pathways, making it a critical research tool in biochemical and pharmacological studies. It is primarily utilized by researchers in pharmaceutical R&D and academic institutions investigating purinergic signaling, inflammation, and neurological disorders.

Application

• Biochemical Research: Used as a selective adenosine kinase inhibitor to study adenosine metabolism and signaling pathways in vitro.
• Pharmacological Studies: Employed in target validation and mechanism-of-action studies for conditions involving purinergic receptors, such as inflammation, pain, and ischemia.
• Neuroscience Research: Applied in models to investigate the role of adenosine in neuroprotection, seizure activity, and sleep regulation.
• Cell Biology: Utilized to modulate intracellular adenosine levels and study its effects on cell proliferation, apoptosis, and immune response.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in analytical laboratories.

Basic Information

Product Name	5-Chlorotubercidin
CAS No.	24386-95-6
Molecular Formula	C11H13ClN4O4
Molecular Weight	300.70 g/mol
Synonyms	7-Deaza-5-chloroadenosine; 4-Amino-5-chloro-7-(β-D-ribofuranosyl)pyrrolo[2,3-d]pyrimidine; 5-Chloro-4-amino-7-β-D-ribofuranosyl-7H-pyrrolo[2,3-d]pyrimidine; NSC 130813; 5-Chloro-tubercidin; 5-Cl-Tubercidin
EINECS	Contact for details

Quality Control

Our 5-Chlorotubercidin is manufactured under a quality management system and undergoes rigorous analytical testing to ensure high purity and batch-to-batch consistency. Standard quality control includes identification by spectroscopic methods (IR, NMR), purity determination by HPLC, and control of related substances. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with each batch.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥98.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.