Description

5-Iodotubercidin is a potent and selective adenosine kinase inhibitor widely used in biochemical and pharmacological research. This compound is valued for its ability to modulate adenosine signaling pathways, making it a critical tool for studying cellular energy metabolism, neuroprotection, and inflammatory responses. It is primarily utilized by researchers and scientists in the pharmaceutical, biotechnology, and academic sectors for drug discovery and mechanistic studies.

Application

• Biochemical Research: As a key reagent for investigating adenosine kinase inhibition and its effects on intracellular adenosine levels.
• Neuropharmacology Studies: For exploring neuroprotective mechanisms and potential therapeutic applications in conditions like ischemia and epilepsy.
• Inflammation and Immunology Research: Used to study the role of adenosine signaling in immune cell regulation and inflammatory processes.
• Cancer Research: Investigated for its effects on tumor cell metabolism and proliferation in various oncological studies.
• Cardiovascular Research: Employed in models examining cardiac preconditioning and ischemia-reperfusion injury.
• High-Throughput Screening (HTS): Serves as a reference standard or active compound in drug discovery assays targeting kinase pathways.

Basic Information

Product Name	5-Iodotubercidin
CAS No.	24386-93-4
Molecular Formula	C11H13IN4O4
Molecular Weight	376.15 g/mol
Synonyms	4-Amino-5-iodo-7-(β-D-ribofuranosyl)pyrrolo[2,3-d]pyrimidine; 7-β-D-Ribofuranosyl-5-iodo-4-aminopyrrolo[2,3-d]pyrimidine; 5-Iodo-7-β-D-ribofuranosyl-4-aminopyrrolo[2,3-d]pyrimidine; ITu; 5-Iodo-tubercidin; NSC 113939; Adenosine Kinase Inhibitor (5-Iodotubercidin)
EINECS	Contact for details

Quality Control

Our 5-Iodotubercidin is produced under strict quality management systems to ensure batch-to-batch consistency and high purity for research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We adhere to relevant industry standards to support your research and development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/IR)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.