Description

L-α-Methylbenzyl Isothiocyanate is a chiral, high-purity organic compound belonging to the isothiocyanate family, characterized by its reactive -N=C=S functional group. This compound is a critical chiral building block and reagent for the synthesis of pharmaceuticals, agrochemicals, and advanced materials, where stereochemical control is paramount. It is essential for research and production in fine chemical synthesis, asymmetric catalysis, and the development of bioactive molecules.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of active pharmaceutical ingredients (APIs), particularly in projects requiring enantioselective synthesis.
• Agrochemical Research: Used in the development of novel pesticides and herbicides, where the chiral center can influence biological activity and selectivity.
• Ligand and Catalyst Preparation: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis.
• Fine Chemical Synthesis: Employed in the multi-step synthesis of complex organic molecules for research and specialty chemical applications.
• Bioconjugation and Probe Development: The reactive isothiocyanate group allows for labeling and conjugation with amines in proteins and other biomolecules for analytical purposes.
• Material Science: Investigated as a monomer or modifying agent for polymers and advanced materials with specific optical or chemical properties.

Basic Information

Product Name	L-α-Methylbenzyl Isothiocyanate
CAS No.	24277-43-8
Molecular Formula	C9H9NS
Molecular Weight	163.24 g/mol
Synonyms	(S)-(-)-α-Methylbenzyl Isothiocyanate; (S)-1-Phenylethyl Isothiocyanate; L-1-Phenylethyl Isothiocyanate; (S)-(-)-1-Phenylethyl Isothiocyanate; (S)-α-Methylbenzyl Isothiocyanate; (S)-PEITC; L-Phenylethyl Isothiocyanate; (S)-1-Phenethyl isothiocyanate
EINECS	Contact for details

Quality Control

Our L-α-Methylbenzyl Isothiocyanate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity (enantiomeric excess) and chemical purity determination by HPLC, GC, and NMR spectroscopy. Certificates of Analysis (COA) detailing all specifications are provided to ensure compliance with your research and production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if necessary to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.