Description

2α,3β,14-Trihydroxy-5α-Cardanolide is a high-purity cardenolide derivative, a class of compounds known for their potent biological activity. This specific stereoisomer is valued for its role as a critical intermediate in advanced pharmaceutical synthesis and biochemical research. It is primarily sought by R&D laboratories and manufacturers in the pharmaceutical and life sciences sectors for developing novel therapeutic agents and conducting structure-activity relationship studies.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel cardiac glycosides and other steroidal drugs.
• Biochemical Research: Used as a reference standard and probe in studies of sodium-potassium ATPase (Na+/K+-ATPase) inhibition and cardiac cell signaling pathways.
• Medicinal Chemistry: Serves as a core scaffold for the development and optimization of new drug candidates targeting heart failure and arrhythmias.
• Academic Research: Employed in university and institutional labs for pharmacological and toxicological studies of cardenolides.
• Reference Material: High-purity grade used for analytical method development, calibration, and quality control in pharmaceutical analysis.

Basic Information

Product Name	2α,3β,14-Trihydroxy-5α-Cardanolide
CAS No.	24211-69-6
Molecular Formula	C23H34O5
Molecular Weight	390.51 g/mol
Synonyms	5α-Card-20(22)-enolide, 2,3,14-trihydroxy-, (2α,3β,5α)-; 2α,3β,14-Trihydroxy-5α-card-20(22)-enolide; 3β,14-Dihydroxy-5α-card-20(22)-enolide-2α-ol; Cardenolide derivative 24211-69-6; 5α-Cardenolide-2α,3β,14-triol; Cardanolide triol
EINECS	Contact for details

Quality Control

Our 2α,3β,14-Trihydroxy-5α-Cardanolide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, identity confirmation by IR and NMR spectroscopy, and tests for residual solvents and moisture to ensure it meets the stringent requirements for pharmaceutical research and development. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.