Description

Cyclobutanecarbonyl Chloride, 3-tert-Butyl-, trans- (8Ci) is a specialized, high-purity organic intermediate featuring a sterically hindered cyclobutane ring system. This compound matters as a critical building block for synthesizing complex molecules in advanced research and development, offering unique structural constraints for modulating molecular properties. It is primarily needed by pharmaceutical and agrochemical R&D teams for the development of novel active ingredients, as well as by specialty chemical manufacturers producing advanced materials and catalysts.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting central nervous system (CNS) or metabolic diseases.
• Agrochemical Synthesis: Used in the research and development of new-generation herbicides, fungicides, and plant growth regulators with enhanced efficacy.
• Advanced Material Precursor: Serves as a monomer or cross-linking agent in the production of specialty polymers and high-performance resins.
• Catalyst Ligand Synthesis: Employed in the preparation of sophisticated chiral ligands for asymmetric catalysis in fine chemical manufacturing.
• Chemical Research & Development: A valuable reagent for academic and industrial research exploring new organic reactions and methodologies.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific, multi-step synthesis projects.

Basic Information

Product Name	Cyclobutanecarbonyl Chloride, 3-tert-Butyl-, trans- (8Ci)
CAS No.	24165-53-5
Molecular Formula	C9H15ClO
Molecular Weight	174.67 g/mol
Synonyms	trans-3-tert-Butylcyclobutanecarbonyl Chloride; 3-(1,1-Dimethylethyl)cyclobutanecarboxylic Acid Chloride, trans-; (1r,3r)-3-tert-Butylcyclobutanecarbonyl Chloride; (1s,3s)-3-tert-Butylcyclobutanecarbonyl Chloride; 3-tert-Butylcyclobutanecarboxylic Acid Chloride; Cyclobutanecarboxylic Acid, 3-(1,1-Dimethylethyl)-, Chloride, trans-; 24165-53-5; trans-3-tert-Butyl-1-cyclobutanecarbonyl Chloride
EINECS	Contact for details

Quality Control

Our production of Cyclobutanecarbonyl Chloride, 3-tert-Butyl-, trans- (8Ci) adheres to stringent quality management protocols. Each batch undergoes rigorous analytical testing, including chromatography (HPLC, GC) and spectroscopic methods (NMR, IR), to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all specified parameters. Our quality system is designed to support cGMP (current Good Manufacturing Practice) requirements for advanced intermediates, ensuring reliability for critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and reacts with strong acids/organic solvents; therefore, it must be kept under an inert atmosphere (e.g., nitrogen or argon) and away from incompatible materials. Keep the container tightly sealed when not in use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Specific Rotation (if chiral)	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.