Description

Cyclobutanecarbonyl Chloride, 3-tert-Butyl-, cis- (8Ci) is a specialized organic acid chloride derivative of cyclobutane, featuring a sterically hindered tert-butyl group in the cis configuration. This compound serves as a critical building block in advanced organic synthesis, enabling the efficient introduction of the sterically demanding 3-tert-butylcyclobutane moiety into target molecules. It is primarily utilized by pharmaceutical research and agrochemical development teams for the synthesis of novel active ingredients and complex intermediates.

Application

• Pharmaceutical Intermediate: Key reagent in the synthesis of novel drug candidates, particularly those requiring sterically hindered cyclobutane scaffolds for enhanced metabolic stability or receptor binding.
• Agrochemical Synthesis: Used in the research and development of new-generation pesticides and herbicides, where the tert-butyl-cyclobutane structure can contribute to unique biological activity.
• Advanced Material Precursor: Serves as a monomer or cross-linking agent in the development of specialty polymers with tailored thermal and mechanical properties.
• Ligand and Catalyst Development: Employed in organic and organometallic chemistry to create sophisticated chiral ligands or catalyst frameworks for asymmetric synthesis.
• Chemical Research & Development: A versatile tool for academic and industrial R&D chemists exploring new reaction methodologies and constructing complex molecular architectures.

Basic Information

Item	Details
Product Name	Cyclobutanecarbonyl Chloride, 3-tert-Butyl-, cis- (8Ci)
CAS No.	24165-52-4
Molecular Formula	C9H15ClO
Molecular Weight	174.67 g/mol
Synonyms	cis-3-tert-Butylcyclobutanecarbonyl Chloride; 3-(1,1-Dimethylethyl)cyclobutanecarbonyl Chloride, cis-; cis-3-tert-Butylcyclobutanecarboxylic Acid Chloride; 3-tert-Butylcyclobutanecarbonyl Chloride (cis-); Cyclobutanecarboxylic acid, 3-(1,1-dimethylethyl)-, chloride, cis-; (cis)-3-tert-Butylcyclobutanecarbonyl Chloride
EINECS	Contact for details

Quality Control

Our Cyclobutanecarbonyl Chloride, 3-tert-Butyl-, cis- (8Ci) is produced under stringent quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and NMR/IR for structural confirmation, to ensure it meets the high standards required for research and process development. Certificates of Analysis (COA) with detailed specifications are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic and moisture-sensitive nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition. Keep away from strong bases, oxidizers, and moisture.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.