Description

Diisopropyl (Ethoxycarbonylmethyl)Phosphonate is a high-purity organophosphorus compound widely recognized as a key Horner-Wadsworth-Emmons (HWE) reagent. This versatile chemical is essential for the efficient synthesis of α,β-unsaturated esters and other valuable olefins via olefination reactions. It is a critical building block for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors, enabling the construction of complex molecular frameworks with precise stereochemical control.

Application

• Pharmaceutical Intermediate Synthesis: A crucial reagent for constructing key olefinic linkages in active pharmaceutical ingredients (APIs), particularly in the synthesis of prostaglandins, retinoids, and other bioactive molecules.
• Agrochemical Manufacturing: Used in the production of advanced crop protection agents, including certain insecticides and fungicides that require specific alkene functionalities.
• Fine Chemical Production: Serves as a fundamental building block in the synthesis of specialty chemicals, flavors, fragrances, and liquid crystals.
• Material Science Research: Employed in the development of novel polymers and organic electronic materials where controlled olefination is required.
• Academic & R&D Laboratories: A staple reagent in organic synthesis for method development and the exploration of new Horner-Wadsworth-Emmons reaction methodologies.

Basic Information

Product Name	Diisopropyl (Ethoxycarbonylmethyl)Phosphonate
CAS No.	24074-26-8
Molecular Formula	C10H21O5P
Molecular Weight	252.24 g/mol
Synonyms	Diisopropyl (ethoxycarbonylmethyl)phosphonate; Diisopropyl (carbethoxymethyl)phosphonate; (Carbethoxymethyl)phosphonic Acid Diisopropyl Ester; Diisopropyl Phosphonoacetate; Diisopropyl (Ethoxycarbonylmethyl)Phosphonate; Diisopropyl 2-(diisopropoxyphosphoryl)acetate; Diisopropyl P,P-bis(1-methylethyl) Phosphonoacetate; HWE Reagent for Ethyl Acrylate
EINECS	Contact for details

Quality Control

Our Diisopropyl (Ethoxycarbonylmethyl)Phosphonate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including NMR, HPLC, and GC analysis, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all specified parameters. Our quality commitment ensures the reagent performs reliably in sensitive synthetic applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong bases and incompatible materials. For long-term storage, consider maintaining under an inert atmosphere to preserve optimal reactivity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Refractive Index (n20D)	1.425 - 1.435
Density (20°C)	1.05 - 1.15 g/mL

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.