Description

Ethyl Isothiocyanatoacetate is a versatile organic synthesis intermediate characterized by its reactive isothiocyanate and ester functional groups. This compound is crucial for the efficient construction of heterocyclic scaffolds and complex molecules in advanced chemical research and development. It is primarily sought after by pharmaceutical, agrochemical, and specialty chemical manufacturers for applications in drug discovery, crop protection, and material science.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of thiazole, thiadiazole, and other nitrogen-sulfur heterocycles with potential biological activity.
• Agrochemical Synthesis: Used in the production of novel herbicides, fungicides, and insecticides, leveraging its reactivity to create active ingredients.
• Peptide Mimetics & Bioconjugation: Serves as a reagent for introducing isothiocyanate groups into molecules for protein labeling or creating peptide analogs.
• Polymer & Material Science: Acts as a monomer or cross-linking agent in the development of specialty polymers with unique thermal or mechanical properties.
• Chemical Research & Development: A valuable tool for medicinal chemists and researchers in exploring new synthetic pathways and molecular entities.
• Dye & Pigment Intermediate: Employed in the synthesis of certain sulfur-containing colorants and functional dyes.

Basic Information

Product Name	Ethyl Isothiocyanatoacetate
CAS No.	24066-82-8
Molecular Formula	C5H7NO2S
Molecular Weight	145.18 g/mol
Synonyms	Ethyl (isothiocyanato)acetate; Acetic acid, 2-isothiocyanato-, ethyl ester; Ethyl 2-isothiocyanatoacetate; Isothiocyanatoacetic Acid Ethyl Ester; NSC 401119; Ethyl isothiocyanatoethanoate; AI3-28430; Ethyl Isothiocyanato Acetate
EINECS	Contact for details

Quality Control

Our Ethyl Isothiocyanatoacetate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chromatographic purity analysis and identity confirmation, to ensure it meets the high standards required for research and industrial synthesis. Certificates of Analysis (COA) detailing purity, assay, and impurity profiles are provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation. Keep away from strong acids and incompatible organic solvents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Refractive Index (n20D)	1.480 - 1.490
Density (20°C)	1.15 - 1.25 g/mL

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.