Description

2',3'-Dideoxyadenosinetriphosphoric acid (ddATP) is a critical nucleotide analog essential for terminating DNA strand elongation in Sanger sequencing methodologies. This compound matters as a foundational reagent for genetic analysis, enabling accurate determination of DNA sequences. It is primarily needed by biotechnology, pharmaceutical, and academic research laboratories engaged in genomics, molecular diagnostics, and drug discovery.

Application

• Sanger DNA Sequencing: Acts as a chain-terminating substrate in dideoxy sequencing reactions.
• Genomic Research: Used in enzymatic DNA synthesis and analysis for studying gene structure and function.
• Molecular Diagnostics: Employed in the development of assays for genetic mutation detection and pathogen identification.
• Drug Discovery & Development: Serves as a tool in target validation and pharmacogenomics studies.
• Forensic Analysis: Utilized in DNA profiling and fingerprinting techniques.
• Biochemical Research: Applied in studies of DNA polymerase kinetics and enzyme mechanism.

Basic Information

Product Name	2',3'-Dideoxyadenosinetriphosphoric acid
CAS No.	24027-80-3
Molecular Formula	C10H16N5O12P3
Molecular Weight	491.17 g/mol
Synonyms	ddATP; 2',3'-Dideoxyadenosine 5'-triphosphate; Dideoxyadenosine triphosphate; Adenosine, 2',3'-dideoxy-, 5'-(tetrahydrogen triphosphate); 2',3'-Dideoxy-ATP; 2',3'-ddATP; 9H-Purin-6-amine, 9-(2,3-dideoxy-5-O-[(hydroxy{[(hydroxy(phosphonooxy)phosphoryl]oxy}phosphoryl)-β-D-glycero-pentofuranosyl]-
EINECS	Contact for details

Quality Control

Our 2',3'-Dideoxyadenosinetriphosphoric acid (ddATP) is manufactured under strict quality systems to ensure high purity and batch-to-batch consistency suitable for sensitive molecular biology applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and performance in sequencing assays. We adhere to ISO 9001 quality management principles, and our production environment is designed to meet the exacting standards of life science research.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability. For long-term storage, desiccate at -20°C.

Specification

Item	Specification
Appearance	White to off-white powder or solid
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 98%
Water Content (Karl Fischer)	≤ 2.0%
pH (1% Solution)	6.0 - 7.5
Biological Activity (Sequencing)	Pass

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.