Description

Articaine CAS NO 23964-58-1 is a potent, amide-type local anesthetic widely recognized for its rapid onset and effective nerve-blocking properties. It is a critical active pharmaceutical ingredient (API) essential for formulating safe and reliable anesthetic solutions. This compound is primarily required by pharmaceutical manufacturers and compounding pharmacies for producing injectable formulations used in dental and minor surgical procedures.

Application

• As the active pharmaceutical ingredient (API) in injectable local anesthetic solutions.
• Formulation of dental cartridges for procedures such as cavity fillings, root canals, and tooth extractions.
• Use in minor outpatient surgical procedures requiring localized pain management.
• Research and development of novel anesthetic delivery systems and pharmaceutical compositions.
• Manufacturing of generic pharmaceutical products containing articaine hydrochloride.

Basic Information

Product Name	Articaine
CAS No.	23964-58-1
Molecular Formula	C13H20N2O3S
Molecular Weight	284.38 g/mol
Synonyms	Articaine Hydrochloride; Carticaine; HOE 045; 4-Methyl-3-[[1-oxo-2-(propylamino)propyl]amino]-2-thiophenecarboxylic Acid, Methyl Ester; 4-Methyl-3-(2-propylaminopropionamido)-2-thiophenecarboxylic Acid Methyl Ester; Methyl 4-methyl-3-[(2-propylaminopropanoyl)amino]thiophene-2-carboxylate
EINECS	Contact for details

Quality Control

Our Articaine is manufactured and tested under strict quality management systems to ensure it meets the high standards required for pharmaceutical use. Each batch undergoes comprehensive analytical testing, including identification, purity assay, and impurity profiling. Certificates of Analysis (COA) documenting compliance with relevant specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms
Identification (HPLC)	Conforms
Assay (HPLC)	98.0% - 102.0%
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%
Residual Solvents (GC)	Complies with ICH Q3C
Heavy Metals	≤ 20 ppm
Loss on Drying	≤ 1.0%
Sulfated Ash	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.