Description

[S,(-)]-2-Methoxypropionyl Chloride CAS NO 23943-98-8 is a high-purity, chiral acid chloride derivative used as a critical building block in advanced organic synthesis. Its primary value lies in its ability to introduce the (S)-2-methoxypropionyl moiety, a key chiral intermediate for constructing complex molecules with defined stereochemistry. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries developing active ingredients, particularly for creating chiral drugs and specialty chemicals.

Application

• Pharmaceutical Intermediate: Key chiral building block for the synthesis of active pharmaceutical ingredients (APIs), especially in stereoselective reactions.
• Agrochemical Synthesis: Used in the production of chiral herbicides, fungicides, and plant growth regulators requiring specific optical activity.
• Peptide & Protein Research: Acts as an acylating agent for modifying amino acids or peptides to introduce chiral methoxypropionyl protecting groups.
• Asymmetric Catalysis: Serves as a precursor for ligands or catalysts used in enantioselective synthesis.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals, flavors, and fragrances where optical purity is critical.
• Material Science: Potential monomer or modifier for creating polymers with specific chiral properties.

Basic Information

Product Name	[S,(-)]-2-Methoxypropionyl Chloride
CAS No.	23943-98-8
Molecular Formula	C4H7ClO2
Molecular Weight	122.55 g/mol
Synonyms	(S)-(-)-2-Methoxypropionyl Chloride; (S)-2-Methoxypropanoic Acid Chloride; L-2-Methoxypropionyl Chloride; (S)-α-Methoxypropionyl Chloride; (2S)-2-Methoxypropanoyl Chloride; (S)-Methoxypropionic Acid Chloride; Optically Active 2-Methoxypropionyl Chloride
EINECS	Contact for details

Quality Control

Our [S,(-)]-2-Methoxypropionyl Chloride is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity analysis by HPLC, to ensure it meets the high standards required for pharmaceutical R&D and production. Certificates of Analysis (COA) detailing identity, purity, enantiomeric excess, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). Due to its nature as a highly volatile and moisture-sensitive strong acid/organic solvent, containers must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent hydrolysis and degradation. Keep away from heat, sparks, open flames, and incompatible materials such as strong bases, alcohols, and amines.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Acid Value	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.