Description

3α,11β-Dihydroxy-5α-Pregnan-20-One is a high-purity steroid derivative with significant importance in pharmaceutical research and development. This compound serves as a critical intermediate or reference standard in the synthesis and analytical profiling of more complex steroid-based active pharmaceutical ingredients (APIs). It is primarily required by pharmaceutical manufacturers, contract research organizations (CROs), and academic institutions engaged in endocrinology research, drug discovery, and the production of specialized therapeutic agents.

Application

• Pharmaceutical Intermediate: A key building block in the multi-step synthesis of advanced steroid hormones and related therapeutic compounds.
• Reference Standard: Used for analytical method development, validation, and quality control (QC) testing in pharmaceutical laboratories to ensure product purity and identity.
• Biochemical Research: Employed in studies investigating steroid metabolism, receptor binding, and enzymatic pathways within endocrinology and metabolic disease research.
• Active Pharmaceutical Ingredient (API) Development: Serves as a precursor in the research and development of new steroid-based APIs targeting various hormonal disorders.

Basic Information

Product Name	3α,11β-Dihydroxy-5α-Pregnan-20-One
CAS No.	23930-29-2
Molecular Formula	C21H34O3
Molecular Weight	334.50 g/mol
Synonyms	3α,11β-Dihydroxy-5α-pregnan-20-one; 5α-Pregnane-3α,11β-diol-20-one; 20-Oxo-5α-pregnane-3α,11β-diol; 3α,11β-Dihydroxy-5α-pregnan-20-one; 11β,3α-Dihydroxy-5α-pregnan-20-one; 5α-Pregnan-3α,11β-diol-20-one
EINECS	Contact for details

Quality Control

Our 3α,11β-Dihydroxy-5α-Pregnan-20-One is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, IR and NMR for structural confirmation, and specific tests for residual solvents and related substances. We provide full traceability and Certificates of Analysis (COA) are available for every shipment, ensuring compliance with your research or cGMP-grade requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.