Description

Trimethyl[[4α-Methylergosta-7,24(28)-Dien-3β-Yl]Oxy]Silane is a sterol-derived organosilicon compound, specifically a silyl ether derivative of a methylergostadiene. This specialized chemical is valued for its role as a key synthetic intermediate and protecting group in advanced organic synthesis. It is primarily utilized by research institutions and industrial R&D departments focused on developing novel pharmaceuticals, agrochemicals, and high-value fine chemicals. The compound's unique structure facilitates complex molecular transformations where precise control over sterol chemistry is required.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of novel steroid-based drug candidates and active pharmaceutical ingredients (APIs).
• Agrochemical Research: Used in the development of new plant growth regulators and fungicides that target sterol biosynthesis pathways.
• Fine Chemical Synthesis: Acts as a versatile intermediate for producing high-value specialty chemicals, including liquid crystals and advanced materials.
• Academic & Industrial R&D: Employed in organic chemistry research for studying sterol transformations and developing new synthetic methodologies.
• Protecting Group Chemistry: The trimethylsilyl (TMS) ether group is utilized to protect hydroxyl functionalities during multi-step synthetic sequences.
• Biochemical Probe Development: Potential use in creating labeled analogs for metabolic pathway studies and biochemical assays.

Basic Information

Product Name	Trimethyl[[4α-Methylergosta-7,24(28)-Dien-3β-Yl]Oxy]Silane
CAS No.	23648-45-5
Molecular Formula	C32H56OSi
Molecular Weight	484.88 g/mol
Synonyms	4α-Methylergosta-7,24(28)-dien-3β-ol trimethylsilyl ether; (3β)-4α-Methylergosta-7,24(28)-dien-3-ol trimethylsilyl ether; 4α-Methyl-5α-ergosta-7,24(28)-dien-3β-yloxytrimethylsilane; Silane, trimethyl[[4α-methylergosta-7,24(28)-dien-3β-yl]oxy]-; TMS ether of 4α-Methylergosta-7,24(28)-dien-3β-ol; 3β-Trimethylsilyloxy-4α-methylergosta-7,24(28)-diene
EINECS	Contact for details

Quality Control

Our Trimethyl[[4α-Methylergosta-7,24(28)-Dien-3β-Yl]Oxy]Silane is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical parameters. Our quality systems are designed to meet the stringent requirements of research and development applications, ensuring reliable performance in your synthetic workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Related Substances (HPLC)	Total impurities ≤ 5.0%
Loss on Drying	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.