Description

2-Trifluoromethyl-Furan-3-Carboxylic Acid Ethyl Ester is a high-value fluorinated heterocyclic building block, prized for its unique trifluoromethyl group which imparts enhanced metabolic stability and lipophilicity to target molecules. This compound is essential for advanced organic synthesis, particularly in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals. It serves as a critical intermediate for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to incorporate fluorine chemistry into their products.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing novel drug candidates, especially in medicinal chemistry programs targeting CNS disorders, anti-inflammatory agents, and antiviral compounds.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the trifluoromethyl group enhances biological activity and environmental stability.
• Material Science Research: Serves as a precursor for developing specialty polymers, liquid crystals, and organic electronic materials with tailored properties.
• Fluorine Chemistry & Catalysis: A valuable reagent in academic and industrial research exploring new fluorination methodologies and catalytic processes.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of complex, fluorinated target molecules under cGMP conditions where applicable.

Basic Information

Product Name	2-Trifluoromethyl-Furan-3-Carboxylic Acid Ethyl Ester
CAS No.	23584-63-6
Molecular Formula	C8H7F3O3
Molecular Weight	208.14 g/mol
Synonyms	Ethyl 2-(trifluoromethyl)furan-3-carboxylate; 3-Furoic acid, 2-(trifluoromethyl)-, ethyl ester; Ethyl 2-trifluoromethyl-3-furoate; 2-Trifluoromethyl-3-furancarboxylic acid ethyl ester; 2-(Trifluoromethyl)-3-furancarboxylic Acid Ethyl Ester; Furan-3-carboxylic acid, 2-(trifluoromethyl)-, ethyl ester; 23584-63-6
EINECS	Contact for details

Quality Control

Our 2-Trifluoromethyl-Furan-3-Carboxylic Acid Ethyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to relevant ISO standards, and we support our clients' needs for regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). Due to its properties as a fluoride/strong alkali and highly volatile compound, ensure containers are sealed when not in use and stored away from incompatible materials. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.