Description

5-Nitrouridine-5'-Monophosphate is a chemically modified nucleotide monophosphate derivative, serving as a critical building block and research reagent in advanced biochemical synthesis. This compound is valued for its role in introducing specific functional groups into nucleic acid structures, enabling the study of structure-activity relationships and the development of novel probes. It is primarily utilized by research institutions and pharmaceutical companies engaged in nucleotide chemistry, medicinal chemistry, and the development of diagnostic tools.

Application

• Nucleic Acid Research: Used as a modified nucleotide precursor in the synthesis of oligonucleotides for studying RNA/DNA structure, function, and interactions.
• Medicinal Chemistry: Serves as an intermediate in the research and development of nucleoside-based antiviral or anticancer therapeutic agents.
• Biochemical Probe Development: Acts as a key component for creating labeled or tagged nucleotides used in diagnostic assays and imaging techniques.
• Enzymology Studies: Employed as a substrate or inhibitor to investigate the activity and specificity of kinases, phosphorylases, and other nucleotide-processing enzymes.
• Academic & Industrial R&D: Essential for fundamental research in bioorganic chemistry and for process development in fine chemical and pharmaceutical manufacturing.

Basic Information

Product Name	5-Nitrouridine-5'-Monophosphate
CAS No.	23568-00-5
Molecular Formula	C9H12N3O11P
Molecular Weight	369.18 g/mol
Synonyms	5-Nitro-UMP; 5-Nitouridine 5'-monophosphate; 5-Nitouridylic acid; Uridine, 5-nitro-, 5'-(dihydrogen phosphate); 5-Nitro-uridine-5'-phosphate; 5-NO2-UMP; 5-Nitroribosyluracil monophosphate
EINECS	Contact for details

Quality Control

Our 5-Nitrouridine-5'-Monophosphate is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research and development applications. A Certificate of Analysis (COA) detailing batch-specific results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/IR)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Heavy Metals	≤ 20 ppm
Solubility	Soluble in water, slightly soluble in methanol

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.