Description

(2-Oxo-1,3-Dioxolan-4-Yl)Methyl Chloroformate is a versatile and highly reactive chloroformate ester derivative, primarily used as a key building block in organic synthesis. Its core value lies in its ability to introduce the reactive chloroformate group into complex molecules, facilitating the synthesis of pharmaceuticals, agrochemicals, and advanced materials. This compound is essential for researchers and manufacturers in the fine chemical, pharmaceutical intermediate, and polymer industries who require a reliable and high-purity reagent for coupling and protecting group chemistry.

Application

• Pharmaceutical Intermediate Synthesis: A critical reagent for the preparation of active pharmaceutical ingredients (APIs), particularly in the synthesis of carbamate and carbonate derivatives.
• Polymer Chemistry: Used as a monomer or cross-linking agent in the production of specialized polymers, including biodegradable materials and polycarbonates.
• Agrochemical Production: Serves as a key intermediate in the manufacture of herbicides, fungicides, and insecticides, where its reactive group is utilized to construct active molecules.
• Peptide & Protein Modification: Employed in bioconjugation chemistry to modify amino acid side chains, such as lysine, for labeling or functionalization.
• Protecting Group Chemistry: Acts as a reagent for introducing acid-labile protecting groups onto alcohols and amines during multi-step synthetic sequences.
• Liquid Crystal & OLED Material Synthesis: A valuable building block for creating advanced organic electronic materials due to its ability to form stable ester linkages.

Basic Information

Product Name	(2-Oxo-1,3-Dioxolan-4-Yl)Methyl Chloroformate
CAS No.	23385-72-0
Molecular Formula	C5H5ClO5
Molecular Weight	180.54 g/mol
Synonyms	4-(Chlorocarbonyloxymethyl)-1,3-dioxolan-2-one; Glycerol Carbonate Chloroformate; 4-(Hydroxymethyl)-1,3-dioxolan-2-one Chloroformate; Carbonochloridic Acid, (2-Oxo-1,3-dioxolan-4-yl)methyl Ester; (4-Methyl-2-oxo-1,3-dioxolan-4-yl)methyl Chloroformate; Glycerol 1,2-Carbonate Chloroformate
EINECS	Contact for details

Quality Control

Our (2-Oxo-1,3-Dioxolan-4-Yl)Methyl Chloroformate is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at 2-8°C. Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition. Keep away from heat, sparks, open flames, and incompatible materials such as strong bases, amines, and alcohols.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Chloride Content	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.