Description

2'-Deoxyadenylyl-(3'-5')-2'-Deoxyadenosine is a defined dinucleotide, a fundamental building block in nucleic acid research and synthesis. This high-purity biochemical is critical for studying DNA structure, enzymatic mechanisms, and for use as a reference standard. It is primarily utilized by researchers and manufacturers in the fields of pharmaceutical development, molecular biology, and diagnostic assay production. Its defined sequence and purity make it an essential reagent for applications requiring precise nucleic acid components.

Application

• Oligonucleotide Synthesis: Serves as a key intermediate or controlled-length standard in the chemical synthesis of DNA strands.
• Enzymology Research: Used as a specific substrate to study the activity, kinetics, and inhibition of nucleases, polymerases, and ligases.
• Biochemical Reference Standard: Provides a characterized benchmark for quality control in molecular biology kits and reagent manufacturing.
• Antisense & Aptamer Development: Acts as a core structural unit in the research and early-stage development of therapeutic oligonucleotides.
• Diagnostic Probe Design: Utilized in the development and calibration of sensitive DNA-based detection assays and hybridization probes.
• Academic Research: Fundamental tool for university and institutional labs investigating DNA biochemistry and molecular genetics.

Basic Information

Product Name	2'-Deoxyadenylyl-(3'-5')-2'-Deoxyadenosine
CAS No.	23339-45-9
Molecular Formula	C20H25N10O10P
Molecular Weight	596.45 g/mol
Synonyms	d(ApA); d(A-A); Deoxyadenylyl-(3'→5')-deoxyadenosine; Adenosine, 2'-deoxyadenylyl-(3'→5')-2'-deoxy-; dA(3'-5')dA; AA dinucleotide (deoxy); 2'-Deoxy-ApA; pd(A-A)
EINECS	Contact for details

Quality Control

Every batch of our biochemicals is produced under strict quality management protocols. We provide comprehensive Certificates of Analysis (COA) detailing purity, identity, and impurity profiles, typically determined by HPLC, NMR, and MS. Our commitment ensures the material meets the exacting standards required for research and development applications. Specifications can be aligned with customer requirements for specific project needs.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the sealed vial to equilibrate to room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 5.0%
Solubility	Soluble in water, DMSO

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.