Description

3Beta-Acetoxy-14Alpha-Carda-5,20(22)-Dienolide is a high-purity, semi-synthetic cardenolide derivative, a key intermediate in advanced pharmaceutical synthesis. This compound is valued for its specific stereochemistry and functional groups, which are critical for developing targeted bioactive molecules. It is primarily sought by research institutions and pharmaceutical manufacturers engaged in the development of novel therapeutic agents, particularly in the fields of cardiology and oncology.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of novel cardiac glycosides and other steroidal drugs.
• Biochemical Research: Used as a reference standard or probe in studies investigating sodium-potassium ATPase (Na⁺/K⁺-ATPase) inhibition and related cellular pathways.
• Medicinal Chemistry: Serves as a core scaffold for structure-activity relationship (SAR) studies to develop new drug candidates with optimized potency and selectivity.
• Academic Research: Employed in university and institutional labs for pharmacological and toxicological studies of cardenolide derivatives.

Basic Information

Product Name	3Beta-Acetoxy-14Alpha-Carda-5,20(22)-Dienolide
CAS No.	23330-61-2
Molecular Formula	C₂₉H₄₂O₅
Molecular Weight	470.64 g/mol
Synonyms	3β-Acetoxy-14α-carda-5,20(22)-dienolide; 14α-Carda-5,20(22)-dienolide, 3β-acetoxy-; (3β,14α)-3-(Acetyloxy)-14-hydroxycarda-5,20(22)-dienolide; 3β-Acetoxy-14α-hydroxycarda-5,20(22)-dienolide; 14α-Hydroxy-3β-acetoxycarda-5,20(22)-dienolide; Card-20(22)-enolide, 3-(acetyloxy)-14-hydroxy-, (3β,5β,14α)-; A key cardenolide acetate intermediate.
EINECS	Contact for details

Quality Control

Our 3Beta-Acetoxy-14Alpha-Carda-5,20(22)-Dienolide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, IR, MS), to ensure it meets exacting standards for research and development use. A detailed Certificate of Analysis (COA) is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Keep away from strong bases and incompatible organic solvents. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.