Description

5-Amino-1-(2-O,3-O,5-o-Triacetyl-β-D-Ribofuranosyl)-1H-Imidazole-4-Carboxamide is a key nucleoside derivative and a crucial advanced intermediate in the synthesis of complex bioactive molecules. Its primary commercial value lies in enabling the production of high-purity, research-grade compounds for pharmaceutical discovery and development. This product is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors who require reliable, high-quality building blocks for nucleoside-based drug candidates and biochemical research.

Application

• Pharmaceutical Intermediate: Critical building block for the synthesis of novel nucleoside analogs and antiviral/anticancer drug candidates.
• Biochemical Research: Used in the study of enzyme mechanisms, metabolic pathways, and as a precursor for labeled compounds in tracer studies.
• Antiviral Agent Development: Serves as a key scaffold in the research and development of potential antiviral therapeutics targeting viral polymerases.
• Nucleoside Chemistry: An essential starting material for organic chemists specializing in carbohydrate and heterocyclic chemistry for further functionalization.
• Reference Standard: Utilized as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.

Basic Information

Product Name	5-Amino-1-(2-O,3-O,5-o-Triacetyl-β-D-Ribofuranosyl)-1H-Imidazole-4-Carboxamide
CAS No.	23274-21-7
Molecular Formula	C15H20N4O8
Molecular Weight	384.34 g/mol
Synonyms	5-Amino-1-(2,3,5-tri-O-acetyl-β-D-ribofuranosyl)imidazole-4-carboxamide; 5-AICA Riboside Triacetate; AICAR Triacetate; Acadesine Triacetate; 5-Aminoimidazole-4-carboxamide-1-β-D-ribofuranoside Triacetate; 5-Amino-1-(2,3,5-tri-O-acetyl-β-D-ribofuranosyl)-1H-imidazole-4-carboxamide; AICAR 2',3',5'-Triacetate
EINECS	Contact for details

Quality Control

Our production of 5-Amino-1-(2-O,3-O,5-o-Triacetyl-β-D-Ribofuranosyl)-1H-Imidazole-4-Carboxamide adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity suitable for research and pharmaceutical applications. All materials are subjected to comprehensive analytical testing, including HPLC, NMR, and mass spectrometry. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.