Description

Trimethoprim Lactate Salt is a high-purity pharmaceutical salt form of the established antibacterial agent, trimethoprim. This compound is critical for ensuring precise formulation stability and bioavailability in finished drug products. It is primarily required by manufacturers in the pharmaceutical and veterinary medicine industries for the production of potent antibacterial formulations.

Application

• Pharmaceutical Intermediates: A key active pharmaceutical ingredient (API) intermediate for synthesizing finished antibacterial drugs.
• Veterinary Medicine: Used in the formulation of antibacterial treatments for livestock and companion animals.
• Combination Therapy: Employed in fixed-dose combination products, often with sulfonamides, for synergistic antibacterial effect.
• Research & Development: Serves as a critical reference standard and raw material in antimicrobial R&D laboratories.
• Urinary Tract Infection (UTI) Treatments: A component in medications targeting gram-negative and gram-positive bacteria causing UTIs.
• Respiratory Infection Formulations: Used in drugs designed to treat bronchitis and other respiratory tract infections.

Basic Information

Product Name	Trimethoprim Lactate Salt
CAS No.	23256-42-0
Molecular Formula	C₁₄H₁₈N₄O₃ • C₃H₆O₃
Molecular Weight	376.40 g/mol
Synonyms	Trimethoprim Lactate; 5-[(3,4,5-Trimethoxyphenyl)methyl]-2,4-pyrimidinediamine Lactate; Lactate Salt of Trimethoprim; TMP Lactate; NSC-106568 (Lactate); Antibacterial BP (Lactate Salt); 2,4-Diamino-5-(3,4,5-trimethoxybenzyl)pyrimidine Lactate
EINECS	Contact for details

Quality Control

Our Trimethoprim Lactate Salt is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for assay and related substances, to ensure it meets high-purity standards suitable for pharmaceutical use. Certificates of Analysis (COA) confirming identity, purity, and compliance with agreed specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water Content (KF)	≤ 1.0%
Related Substances (HPLC)	Total impurities ≤ 1.0%; Any single impurity ≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.