Description

8-Fluoroadenosine is a fluorinated nucleoside analog, a key building block in medicinal chemistry and biochemical research. Its value lies in its role as a versatile intermediate for synthesizing modified oligonucleotides and potential pharmaceutical agents, particularly in antiviral and anticancer drug discovery. This compound is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and diagnostic reagent sectors who require high-purity, specialty nucleosides for advanced applications.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel antiviral and anticancer nucleoside analogs.
• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies to investigate nucleotide metabolism and related pathways.
• Probe Development: Serves as a building block for creating fluorescent or radiolabeled probes for molecular biology and diagnostic assays.
• Antisense Oligonucleotide Synthesis: Incorporated into oligonucleotide sequences to modulate stability, binding affinity, and biological activity.
• Chemical Biology Tool: Employed to study RNA function and structure through site-specific incorporation into nucleic acids.
• Reference Standard: Used as a high-purity analytical standard in quality control laboratories for method development and validation.

Basic Information

Product Name	8-Fluoroadenosine
CAS No.	23205-67-6
Molecular Formula	C10H12FN5O4
Molecular Weight	285.23 g/mol
Synonyms	8-Fluoroadenosine; 9-β-D-Ribofuranosyl-8-fluoroadenine; 8-Fluoro-9-β-D-ribofuranosyl-9H-purin-6-amine; 8-F-Ade; 8-Fluoroadenosine riboside; Adenosine, 8-fluoro-; 8-Fluoroadenosine (8-FA)
EINECS	Contact for details

Quality Control

Our 8-Fluoroadenosine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for research and pharmaceutical development. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.